Senior Principal Scientist, Lab Head, Type Immunology

About the Job

Job Title:

Senior Principal Scientist, Lab Head, Type 2 Immunology

Location:

Cambridge, MA

About the Job Are you ready to shape the future of medicine? The race is on to speed up drug discovery and development to find answers for patients and their families. Sanofi is seeking an accomplished, visionary, and strategic scientific leader to join our Immunology & Inflammation Research Therapeutic Area as a Lab Head at the Director level. This pivotal role will be instrumental in shaping and advancing our innovative portfolio aimed at discovering and developing transformative therapies for immune-mediated diseases.

The successful candidate will lead a dedicated research laboratory, providing scientific and strategic leadership, fostering a culture of high performance and innovation, and driving drug discovery programs from novel target identification through to preclinical development. This position demands deep expertise in Type 2 immunology, a strong track record of scientific achievement, and proven leadership capabilities in a drug discovery setting.

The successful candidate will have an opportunity to leverage Sanofi’s vast Drug Discovery Toolbox and application of AI, at scale, to contribute significantly to the research efforts directed towards developing new therapeutics. Research activities will be broad with the ideal candidate having strong technical expertise in both murine and human immunology. The position will initially support our pre-clinical portfolio, supporting the generation of high quality, robust data packages for transition to early clinical development teams across dermatology, gastroenterology, respiratory and rheumatology.

This role will involve guiding matrix and local teams in in partnership with our Discovery Platform colleagues as well as teams in Development, Medical Affairs and Commercial to drive our research directions and maximize the value of these innovations. The successful candidate will have an opportunity to leverage Sanofi’s vast technical toolbox and application of AI, at scale, to contribute significantly new and existing projects.

Research activities will be broad with the ideal candidate having strong technical expertise in both murine and human immunology. A successful candidate should be experienced with novel assay development (both in vitro and in vivo) and have a track record in immunological and disease pathway exploration. Technical expertise in imaging, cell-based assays, molecular techniques (including single cell approaches), and multi-omic based technologies will be necessary to further our research ambitions.

The candidate should be able to scientifically lead and execute research work, analyze, and present data, and have an ability to utilize excellent technical, written, and oral communication skills (across both expert and non-expert audiences), and effectively collaborate in a team environment. Experience with mentoring junior members of teams is preferable. A successful candidate should be curious in exploring new paths for scientific discoveries and bold in proposing creative experimental designs and ideas.

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?

• Scientific and Strategic Leadership:
  Provide expert scientific vision, strategic direction, and operational leadership for a research laboratory focused on identifying and validating novel therapeutic targets and advancing drug discovery programs in immunology and inflammation.
• Team Leadership and Development:
  Lead, mentor, and develop a team of scientists and researchers, fostering a culture of scientific excellence, innovation, collaboration, and urgency. Manage team performance and resource allocation.
• Portfolio Delivery:
  Drive the progression of immunology projects from target discovery and validation through to candidate selection and IND-enabling studies.…