Scientist I​/II

We think differently, act boldly, and push boundaries in pursuit of new heights. We’re building a team of scientists and drug developers committed to translating the field of up regulation into transformative medicines.

The journey is exhilarating. The view from the top is breathtaking. Join us at the forefront.

Pioneering a new approach to up regulate genes

To change the lives of countless patients with diseases caused by inadequate gene expression

Push boundaries and pursue breakthroughs.

Adapt quickly to challenges and opportunities.

Turn curiosity into trailblazing science.

Lead with empathy and embrace diverse perspectives.

Act urgently. Patients are waiting.

If you want to be part of a company that is growing, nimble, and intent on changing the world, join the adventure that is CAMP4!

CAMP4 values the strength that diversity brings to the workplace. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, religion, color, sex, gender identity, sexual orientation, age, non-disqualifying physical or mental disability, national origin, veteran status or any other characteristic protected by applicable law.

Position:Scientist I/II

Location: Cambridge, MA

Job :312

# of Openings:1

Position Title:Scientist I/II
Reports To:Director, Discovery
Location:Watertown, MA

Join the adventure!
CAMP4 is seeking a highly motivated Scientist to join our Discovery team and contribute to the advancement of CNS programs from target selection through candidate nomination. This is an excellent opportunity for a recent PhD graduate with a strong background in neuroscience or a related discipline who is interested in applying functional neuroscience approaches to drug discovery. A primary responsibility of this role will be to develop and establish functional and phenotypic assays in human iPSC-derived neuronal models to support target validation and characterize the activity of candidate ASOs.

The successful candidate will apply approaches such as multielectrode array (MEA), calcium imaging, and high-content imaging to characterize disease-relevant neuronal phenotypes and to evaluate rescue by candidate ASO.

The Scientist will work closely with members of the Discovery team as well as cross-functional colleagues in Platform, Chemistry, Preclinical and Data Science. We are looking for a curious, rigorous, and collaborative Scientist who enjoys developing new experimental approaches and translating biological questions into robust cellular assays.

Key Responsibilities:

• Develop, optimize, and implement functional and phenotypic assays in human iPSC-derived neurons, including multielectrode array (MEA), calcium imaging, and high-content imaging.
• Establish disease-relevant neuronal phenotypes in patient iPSC-derived neurons and evaluate functional responses to candidate ASOs.
• Design and execute experiments supporting target validation though candidate selection across CNS discovery programs.
• Develop cellular and biochemical assays to assess target engagement and downstream biological effects of ASOs.
• Analyze, interpret, and communicate experimental results to project teams and broader scientific audiences.
• Collaborate with cross-functional scientists to integrate functional assay results with molecular, genomic, and pharmacological data to drive project advancement to key go/no-go decisions.
• Maintain accurate and detailed experimental records to support regulatory documentation of candidate ASOs.

• PhD in neuroscience, molecular biology, cell biology, or a related discipline with 0-3 years of post-degree experience.
• Hands‑on experience with neuronal…