Senior Scientist – Immunology and biotherapeutics
Listed on 2026-10-06
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Research/Development
Immunology Research, Research Scientist, Biotech Research
Senior Scientist leading immunology studies to evaluate biotherapeutic modalities, including antibody-oligonucleotide conjugates (AOCs) and xRNA approaches, focusing on immune profiling and immunogenicity assessment.
Responsibilitiesdesign and execute complex immune assays using primary cells, analyze immune cell activation, cytokine release, innate and adaptive responses, generate mechanistic data for candidate optimization, biomarker development, and safety evaluation; collaborate across disciplines such as oligonucleotide biology, bioanalytics, toxicology, and disease biology; communicate findings to project teams.
RequirementsPh.D. (0-1 year) or MSc in Life Sciences with 2-5 years research experience in human immunology or cell biology; expertise in immune assay development, primary immune cells, flow cytometry, qPCR, transcriptomics, and immune response assessment; strong data analysis and experimental design skills.
Preferredknowledge of xRNA biotherapeutics, AOCs, or antibody delivery platforms; experience with orthogonal omics data analysis is a plus.
High-Valuefocus on immunogenicity and immune pathway interactions of novel biologics, particularly in early discovery or translational stages.
Work setupon-site in Cambridge, MA, with no relocation support.
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