Sr. Scientist, Immunology

Job Description

Join our Immunology team in Cambridge, Massachusetts, and help shape the future of treatments for inflammatory and autoimmune diseases. At our company, we are at the forefront of immunology research, translating scientific advances into meaningful clinical impact. This is an opportunity to work in a dynamic environment where you will evaluate and apply novel experimental approaches, partnering across departments to implement cutting-edge laboratory technologies.

Your contributions will directly impact the development of new therapies and medicines that improve patient lives.

• Design and execute experiments, analyze and interpret complex datasets to identify and validate novel targets in immunology, inflammation, autoimmunity, and fibrosis
• Apply knowledge of key signal transduction pathways to design appropriate experiments
• Be a key contributor in lab and in meetings to progress multiple programs
• Conceptualize and enact innovative approaches (including novel technologies) to address and solve program objectives and issues
• Design, execute, and troubleshoot cell-based functional assays, including routine tissue culture, cytokine profiling, extracellular matrix immunofluorescence staining, and cellular potency readouts
• Isolate and characterize primary immune cells and perform translational assay systems, including PBMC and whole-blood assays
• Manage project‑specific milestones and timelines
• Communicate science and strategy to stakeholders and management
• Collaborate effectively both internally and externally, within and across functional areas
• Demonstrate a “one-team” mindset by proactively engaging in and leading lab and department initiatives
• Actively participate in cultural initiatives, embrace DE&I principles, promote psychological safety, and support a work environment that positively influences others and enables all to bring their true selves to work

• B.Sc. in Biological Sciences, Immunology, Pathology, Biochemistry, Biotechnology, Biomedical Engineering, or related STEM discipline with 7+ years of research experience, M.Sc. with 4+ years of research experience, or PhD and 0+ years of experience.
• Deep knowledge of inflammatory, autoimmune, and/or fibrotic disease mechanisms
• Hands‑on experience in developing, optimizing, and troubleshooting cellular immunology assays, ideally using primary human immune and/or stromal cell systems
• Practical experience in designing and executing complex cellular systems and/or co‑culture models
• Strong ability to interpret data from biological, biochemical, and immunological assays and to design appropriate follow‑up experiments

• Experience with primary stromal cell cultures and developing in vitro models of fibrosis
• Familiarity with immunofluorescence microscopy/high‑content imaging

Required Skills: Assay Development, Autoimmune Diseases, Cell Culture Techniques, Cellular Immunology, Cytokines, Drug Target Identification, Fibroblasts, Fibrosis, Flow Cytometry, High Content Screening, Immunoassays, Immunology, Immunomodulation, Immunophenotyping, Inflammatory Diseases, Innate Immunity, Molecular Biology

Preferred

Skills:

Transcriptomics

#EligibleforERP

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