Director, Bioconjugation
Listed on 2026-10-16
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Research/Development
Biotech Research, Regulatory Compliance Specialist, Drug Discovery, Research Scientist -
Pharmaceutical
Regulatory Compliance Specialist, Drug Discovery
Senior scientific leader as Director of Bioconjugation, focusing on antibody-drug conjugates (ADCs) and antibody-RNA conjugates (ARCs/AOCs).
ObjectivesDefining bioconjugation strategies, leading a team of scientists, partnering across disciplines to advance conjugate therapeutics from target selection through candidate nomination and transition to development.
ResponsibilitiesSetting the bioconjugation platform strategy; overseeing chemistry, linker-payload design, and conjugation technology; managing external collaborations.
RequirementsPhD in chemistry, biochemistry, or related, with 8+ years in industry or academia, including at least 6 years in leadership roles. Deep expertise in bioconjugation chemistry—cysteine/lysine conjugation, site-specific and enzymatic methods, click chemistry—and experience with cytotoxic payloads, oligonucleotide conjugates, and degrader platforms. Proven track record in advancing discovery programs to clinical candidates, with strong analytical skills (RP-HPLC, SEC, LC-MS).
Preferred qualificationsLeadership in discovery project teams, oligonucleotide therapeutics, glycan-mediated platforms, and CMC/tech transfer experience supporting IND-enabling packages.
High-value specificsAntibody conjugates, payload diversity (small molecules, oligonucleotides, degraders), therapeutic areas, and portfolio strategy.
CollaborationCross-functional with Discovery Chemistry, Biology, DMPK, Toxicology, and external partners.
Work setupLocation not explicitly specified, likely hybrid or onsite given the role's strategic leadership and collaboration scope.
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