Scientist, Sequencing and Plate- Assays

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits.

This is work that transforms the lives of patients, and the careers of those who do it.

Position Summary Bristol Myers Squibb is seeking a motivated and detail-oriented (Senior) Scientist to join our Analytical Development team. In this role, you will develop new analytical methods for the characterization of RNA therapeutics, and support routine and non‑routine analytical testing activities critical to the advancement of our in vivo non‑viral drug discovery and development pipeline. The ideal candidate possesses hands‑on laboratory experience, a strong scientific foundation, and a commitment to data quality and compliance.

• Develop sequencing (both NGS and Sanger) and qPCR methods for RNA therapeutics
• Develop plate‑based assays (e.g. ELISA, MSD)
• Explore new techniques and technologies to characterize RNA
• Analyze, interpret, and summarize experimental data with accuracy; prepare clear and concise lab reports and technical summaries
• Contribute to writing regulatory documents, method protocols and reports
• Train and mentor junior team members
• Execute and document laboratory experiments according to established SOPs, protocols, and Good Laboratory Practice (GLP) standards
• Maintain laboratory equipment including calibration, troubleshooting, and coordination with vendors for preventive maintenance
• Ensure compliance with all safety regulations, environmental health and safety (EHS) guidelines, and BMS corporate policies
• Contribute to cross‑functional teams, collaborating with colleagues in research, process development, and formulations

• PhD in Biochemistry, Chemistry, Biology, Pharmaceutical Sciences, or a related scientific discipline. 3–8 years of hands‑on laboratory experience, preferably with RNA and/or LNPs, including academic research, internships, or industry roles.
• Proficiency with NGS and Sanger sequencing (sample preparation, instrumentation and data analysis)
• Proficiency with plate‑based assays (qPCR, digital PCR, ELISA and others).
• Demonstrated ability to work independently and manage multiple priorities in a fast‑paced environment while maintaining accuracy and attention to detail.
• Demonstrated ability to analyze data and present results to the team and the larger research community.

• Experience in a pharmaceutical or biopharmaceutical industry setting.
• Familiarity with QbD principles, ICH guidelines, analytical method lifecycle, GxP principles, and regulatory submission requirements.
• Experience with LIMS (Laboratory Information Management Systems) is a plus.
• Experience with (bio) analytical method validation (e.g., per FDA or EMA guidelines).
• Working knowledge of statistical analysis tools (e.g., Graph Pad Prism, JMP, or Excel‑based analysis).
• Experience with RNA characterization techniques (e.g., RT‑PCR, RNAseq, SEC, CE).

Cambridge - MA - US: $106,010 - $128,462 The starting pay range(s) listed above is for full‑time employees (FTE). You may also be eligible for additional discretionary incentive cash and stock opportunities. We determine starting pay thoughtfully – carefully considering the nature of the role, required skills, work location, schedule and the knowledge and experience you bring. Final compensation is guided by pay equity principles and…