Senior Scientist , Experimental & Systems Immunology

• Full-time
• Salary Min: 96500
• Therapy Area:
  Immunology
• Salary Max: 183500
• Workday Global Grade: 17
• Travel:
  Yes, 5% of the Time
• Compensation: USD 96,500 - USD 183,500 - yearly

About Abb Vie

Abb Vie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about Abb Vie, please visit us at  .

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Abb Vie's Immunology Discovery organization is seeking a highly motivated Senior Scientist I to join our Immune Profiling Systems Immunology team within the Discovery Immunology organization in Cambridge, Massachusetts. The successful candidate will contribute to the identification, validation, and prioritization of novel therapeutic targets for autoimmune and inflammatory diseases through the integration of experimental immunology and quantitative data analysis.

This role is ideal for a scientist who enjoys working at the interface of wet-laboratory experimentation and computational analysis. The candidate will design and execute human disease-relevant experiments, with an emphasis on complex in vitro models such as organoids or complex co-culture systems and their characterization using a range of high-throughput methodologies. They will generate high-dimensional datasets, analyze and interpret results, and collaborate across multidisciplinary teams to advance discovery programs and portfolio decisions.

• Design, execute, and interpret immunology-focused experiments using primary human cells, PBMCs, tissues, and disease-relevant model systems.
• Design and execute studies using complex in vitro models, including organoids or complex co-culture systems, and characterize these models using a range of high-throughput methodologies, such as multiplexed assays and sequencing-based profiling.
• Develop and implement assays to characterize immune cell function, signaling pathways, cellular phenotypes, and therapeutic mechanisms of action.
• Generate and analyze data from flow cytometry, cytokine profiling, NGS-based approaches, single-cell and spatial profiling workflows, and other molecular profiling platforms.
• Partner with computational biologists, bioinformaticians, translational scientists, and disease-area teams to develop mechanistic insights and prioritize therapeutic targets.
• Apply statistical and computational approaches to analyze complex datasets and communicate findings clearly to multidisciplinary audiences.
• Maintain accurate experimental records and contribute to scientific reports, presentations, and project reviews.
• Stay current with advances in immunology, translational research, systems biology, and emerging technologies and incorporate new approaches into discovery programs.
• Present findings to project teams, leadership, and external scientific forums as appropriate.
• Contribute to the scientific culture through collaboration, mentorship of junior scientists, and sharing of technical expertise.

• BS/BA, MS, or PhD inin Immunology, Molecular Biology, Cell Biology, or a related scientific discipline with typically0-3+ (PhD), 8-9+ (MS), or 10-11+ (BS) years of relevant academic and/or industry experience.
• Strong scientific background in immunology and immune-mediated diseases.
• Demonstrated expertise in experimental design, execution, and interpretation.
• Hands-on experience working with primary human samples, including PBMCs, tissues, or disease-relevant cellular…