FL| Cambridge, MA FLSenior Research Associate, Genomics

Cambridge, MA USA

FL114 is an innovative, privately held biotechnology company developing our novel epigenetic editing platform to treat a variety of diseases through precise, tunable
modification of gene expression
. FL114 was founded by Flagship Pioneering, where companies such as Moderna Therapeutics (NASDAQ: MRNA) and Seres Therapeutics (NASDAQ: MCRB) were conceived and created. With a strong emphasis on innovation and experimental execution, FL114 cultivates a highly dynamic and entrepreneurial environment
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FL114, Inc. is seeking an outstanding Senior Research Associate to join our Genomics team. We’re looking for a skilled, NGS-focused molecular biologist to assist in the development and advancement of our epigenetic editing programs, from early discovery research to preclinical development and beyond. The successful candidate will be an essential member of a close-knit team of experimental and computational scientists. We are looking for enthusiastic, detail oriented, adaptive, and highly motivated individuals with a passion for bringing novel medicines to patients.

Applicants should be comfortable working on a fast-paced, cross-functional scientific team.

• Execution of NGS-based functional genomics assays in a high-throughput production environment that address core R&D needs in cell state mapping and therapeutic molecular validation
• Collaborate with research teams to help develop and support fit-for-purpose NGS solutions and molecular and cellular assay technologies
• Contribute to the development and execution of specialized molecular assays

• 2+ years of hands-on experience performing NGS library prep for Illumina platforms
  • Familiarity with ATAC-seq, RNA-seq, ChIP-seq, Methyl-Seq, and/or 10X Single-cell
  • Direct experience operating Illumina instruments
• Familiarity with liquid handlers and Kingfisher automation
• Proficiency with quantification/QC platforms (Qubit, Tape Station/Bio Analyzer)
• Hands-on experience with core molecular biology techniques such as nucleic acid extraction/purification, PCR/qPCR, restriction digestion/ligation
• Comfortable troubleshooting and optimizing assays/protocols
• Experience in an industrial, drug-development environment preferred
• Experience in immunological indications preferred

Flagship Pioneering is a scientific innovation engine that invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps in human health, sustainability, and beyond.
What sets Flagship apart is our ability to advance biotechnology by uniting life science innovation, company creation, and capital investment under one roof in a way that islargely without precedent. Our team of scientists, entrepreneurial leaders, and professional capital managers are eachaligned around an institutionalized process that enables us to innovate and create breakthroughs for the benefit of people andplanet. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.
Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been named four times to Fast Company’s annual list of the World’s Most Innovative Companies.

At Flagship, we recognize there is no…