Enterprise Architect; office locations

Position: Enterprise Architect  (we have office locations  and )
Company Description

Genomics England is a global leader in enabling genomic medicine and research, focused on creating a world where everyone benefits from genomic healthcare. Building on the 100,000 Genomes Project, we support the NHS’s world-first national whole genome sequencing service and run the growing National Genomic Research Library, alongside delivering numerous major genomics initiatives. By connecting research and clinical care at national scale, we enable immediate healthcare benefits and advances for the future.

Our mission is to provide the evidence and digital systems so that by 2035 genomics could play a role in up to half of all healthcare interactions, whilst securing the UK’s position as the best place to discover, prove and benefit from genomic innovations.

We are accelerating our impact and working with patients, doctors, scientists, government and industry to improve genomic testing, and help researchers access the health data and technology they need to make new medical discoveries and create more effective, targeted medicines for everybody.

Behind the Healthcare and Research outcomes, Genomics England delivers through designing, developing and operating complex healthcare software systems.

We're on the cusp of big changes with the real prospect of genomics becoming the fabric of everyday healthcare through the lifetime - from birth to old age.

Job Description

Genomics England are hiring an Enterprise Architect.

You will work across Genomics England, shaping the enterprise architecture vision, strategy, and roadmaps for business and technology capabilities across the organisation, including clinical and diagnostic services, research and discovery platforms, data and digital capabilities, and corporate functions.

In this role, you will work closely with business leaders, service designers, user researchers, product managers, engineers, security, data, and third-party suppliers to shape strategic direction, align investment to target architectures, and ensure a coherent approach across enterprise and corporate platforms.

The role will form part of an enterprise architecture team, helping define enterprise-wide principles, policies, standards, target states, transition roadmaps, and reusable patterns, while ensuring change across Genomics England aligns with broader organisational strategy, governance, and architecture principles.

As an experienced Enterprise Architect, you bring expertise in enterprise architecture leadership, helping teams and stakeholders make effective strategic choices, understand dependencies and trade-offs, and evolve capabilities in a way that is sustainable, coherent, and aligned to successful business outcomes.

Work with the wider enterprise architecture team to define and maintain target enterprise architectures, principles, and roadmaps across clinical, research, data, digital, and corporate capabilities, ensuring alignment to organisational strategy and priorities.

Provide enterprise architecture leadership across Genomics England, shaping a coherent technology and capability landscape across business functions.

Develop enterprise-wide architecture views across business, data, applications, integrations, and technology platforms.

Work with senior stakeholders to translate business strategy into target states, investment priorities, and phased transition plans.

Establish and promote architecture standards, reference models, reusable patterns, and governance approaches that support consistency and informed decision-making.

Assess current-state architecture, identify duplication, risk, complexity, and opportunities for rationalisation or improvement across enterprise and SaaS platforms.

Guide major initiatives and programmes to ensure solutions align with enterprise architecture principles, strategic roadmaps, and intended business outcomes.

Collaborate with security, data, engineering, delivery, and procurement teams to ensure architecture decisions reflect regulatory, operational, financial, and technical considerations.

Work with vendors and third-party providers to assess strategic fit, support product selection, and shape sustainable…