Chief Enterprise Architect

UK, USA, Spain & India

The Chief Enterprise Architect shapes AstraZeneca’s technology future. Working at the intersection of science, data, AI and engineering, the role drives the evolution of AstraZeneca’s digital ecosystem so that technology accelerates the discovery, development and delivery of medicines. The role provides strategic technology leadership across platforms, data, AI, cloud and digital products, while enabling autonomous teams to innovate safely and her than acting as a central control point, the role establishes clear technology principles, reusable platforms and lightweight guardrails that help teams move faster, reduce complexity and deliver measurable business and patient impact.

The role is accountable for shaping a modern, product- and platform-oriented technology architecture across AstraZeneca.

• Define AstraZeneca’s enterprise technology strategy, technology principles and strategic investment priorities.
• Establish lightweight architectural guardrails that enable teams to move quickly while maintaining enterprise coherence.
• Simplify decision‑making, reduce organisational friction and remove unnecessary architecture bureaucracy.
• Advise the CIO, Executive Leadership Team and senior business leaders on strategic technology choices.

• Define AstraZeneca’s enterprise AI architecture and technology strategy, including generative AI, agents, machine learning and advanced analytics.
• Establish reusable AI platforms, services and patterns that can be adopted safely across R&D, clinical, operations, commercial and corporate functions.
• Partner with scientific, clinical and commercial teams to unlock AI‑driven value while ensuring security, compliance and measurable outcomes.

• Build and evolve enterprise platforms that accelerate delivery and reduce duplication.
• Champion platform engineering, API‑first architecture, self‑service capabilities and a strong internal developer experience.
• Reduce cognitive load on product and engineering teams by creating reusable technology capabilities.

• Shape multi‑year transformation programmes around business outcomes, product delivery and value creation.
• Ensure technology platforms support AstraZeneca’s priorities across R&D, Clinical Development, Manufacturing, Commercial and Corporate Functions.
• Drive modernisation and rationalisation where it improves speed, resilience, cost or user experience.

• Embed security, privacy, resilience, GxP and regulatory compliance into technology design without slowing delivery unnecessarily.
• Make balanced risk decisions that support innovation in a regulated environment.

• Build a world‑class technology strategy and architecture community across AstraZeneca.
• Attract and develop exceptional architects, engineers and product‑minded technology leaders.
• Foster a culture of curiosity, experimentation, simplicity, collaboration and speed‑to‑value.

• Increased reuse of enterprise platforms and shared capabilities.
• Faster technology decision‑making and reduced delivery friction.
• Greater adoption of AI capabilities across the enterprise.
• Improved developer productivity and internal customer experience.
• Reduced technology complexity, duplication and avoidable cost.
• Clearer link between technology investment and business, scientific and patient outcomes.

• Significant senior technology leadership experience in a global, complex organisation
• Experience shaping technology strategy across cloud, data, AI, platforms and digital products
• Track record of…