SENIOR Scientist – Translational Biology; FTC

SENIOR SCIENTIST – TRANSLATIONAL BIOLOGY

12 month FTC (Maternity Cover)

About the Role

We are seeking a highly organised and proactive Senior Scientist with deep expertise in human immunology to join our Translational Biology team on a fixed term basis. Reporting to the Director of Translational Biology, the successful candidate will be responsible for developing disease relevant in vitro/ex vivo models and delivering data packages to support MOA studies and indication selection. The ideal candidate will play a key role in our drug discovery efforts and contribute to achieving our ambitious goals.

We value individuals who thrive in a dynamic environment and adapt to our agile and fast-paced work culture.

• Develop and establish in vitro and ex vivo models of immune-related diseases using primary material.
• Characterise the pharmacology and MOA of lead Knot Bodies in primary immunology models
• Contribute to wider translational activities including in vivo study design and interpretation.
• Analyse, interpret and effectively communicate data verbally and in written form to team members.
• Solve problems and troubleshoot on a day-to-day basis.
• Maintain accurate records of all work by completing laboratory notebooks on time, following Company procedures.

• PhD in Immunology, pharmacology or related field. Relevant postdoctoral or industrial experience is essential.
• Previous experience with primary human PBMCs and tissue, and proficiency with assays for antibody/biologic characterisation including cell binding, activation and proliferation.
• Technical expertise in primary cell culture and tissue dissociation, multicolour flow cytometry and cell sorting, ELISA/MSD.
• Actively contributes to a vibrant and innovative working environment where improvements and new ideas are adopted and freely shared among the teams.
• Has the desire and ability to work in a fast-paced, quickly changing environment, showing agility/flexibility to meet deadlines and goals and with a can-do attitude.

• A competitive salary based on experience
• A comprehensive benefits package including generous pension contribution, Private Life and Medical Insurance and a Cycle to Work Scheme.
• Located in a state‑of‑the‑art Science Park with easy access to Cambridge by car, train and bus, and offering on‑site gym, cafe, and a vibrant social community.
• Working alongside an innovative team of scientists, including the founders, who are Key Opinion Leaders in the field.
• A supportive work environment with a key focus on fostering collaborative working environment within a friendly team.