Research Assistant Renal Organoids GSK Translational Immunology Collab

Overview

We are seeking a talented research assistant to build and optimise human iPSC‑derived renal organoids, using them as a platform to decode the molecular mechanisms behind chronic kidney disease (CKD). This exciting translational role sits at the intersection of innovative stem cell engineering and disease modelling, targeting genetic, metabolic, and immune‑driven pathologies.

The research forms part of the Cambridge‑GSK Translational Immunology Collaboration (CG‑TIC), a five‑year partnership between the University of Cambridge and GSK. It will be conducted in the Department of Medicine, working in the lab of Prof. David Thomas within the Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID). You will also spend time in the research group of Prof. Katja Röper (Department of Physiology, Development and Neuroscience) and interact with GSK partners.

• Build and optimise human iPSC‑derived renal organoids using proven kidney organoid frameworks.
• Simulate disease states via targeted perturbations, including genetic variants, metabolic stress, and inflammatory cues.
• Map downstream phenotypes using a broad suite of laboratory techniques.
• Collaborate across research groups to advance understanding of immune‑mediated kidney and respiratory diseases.

• Degree (MSc) in a relevant scientific discipline (e.g., molecular biology, biomedical sciences).
• Significant laboratory experience with sterile cell culture.
• Experience with CRISPR‑Cas9 gene editing and/or organoid systems is highly desirable but not essential.
• Strong scientific curiosity and interest in pursuing PhD‑level research.

• Full‑time position with consideration for fewer than full‑time hours.
• Flexible and family‑friendly working patterns; open to non‑standard and part‑time arrangements.
• Opportunity to travel to Cambridge for collaboration.
• Potential scope for project development towards doctoral research training.

Funds for this position are available until 10th October 2029.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.