Software Engineer - Python & AWS; office locations

Genomics England is a global leader in enabling genomic medicine and research, focused on creating a world where everyone benefits from genomic healthcare. Building on the 100,000 Genomes Project, we support the NHS’s world-first national whole genome sequencing service and run the growing National Genomic Research Library, alongside delivering numerous major genomics initiatives. By connecting research and clinical care at national scale, we enable immediate healthcare benefits and advances for the future.

Our mission is to provide the evidence and digital systems so that by 2035 genomics could play a role in up to half of all healthcare interactions, whilst securing the UK’s position as the best place to discover, prove and benefit from genomic innovations.

We are accelerating our impact and working with patients, doctors, scientists, government and industry to improve genomic testing, and help researchers access the health data and technology they need to make new medical discoveries and create more effective, targeted medicines for everybody.

Behind the Healthcare and Research outcomes, Genomics England delivers through designing, developing and operating complex healthcare software systems.

We're on the cusp of big changes with the real prospect of genomics becoming the fabric of everyday healthcare through the lifetime - from birth to old age.

Software Engineer - Python & AWS

Genomics England is hiring an experienced Software Engineer with strong Python and AWS experience to join our Scientific R&D team, which sits within our Generate Research Data (GRD) service. GRD works across our organisation and with external partners to generate, obtain and enrich high-quality genomic, multi-omic and clinical datasets.

The service supports the journey from new research studies and emerging technologies through to preparing data for release into the National Genomic Research Library (NGRL), helping enable research, discovery and clinical impact.

The Scientific R&D team develops and tests new genomic and multi-omic approaches and provides scientific expertise across GRD. The team operates wet-lab and bioinformatics capabilities, including long-read sequencing, data analysis, technology assessment and pilot development. It supports programmes such as Cancer 2.0 and Generation Study-related discovery work, while investigating how emerging technologies can be applied to future research.

This Software Engineer role develops and maintains data processing systems within the Scientific R&D team, working across a mixture of cloud and on-premises infrastructure to support the assessment of cutting-edge sequencing technologies for clinical genome sequencing.

What you’ll be doing:

Thinking through, designing and enabling the future facing research cohorts end to end

Writing clean, scalable Python code, following engineering best practices

Developing working solutions to enable processing of long read data, including future facing solutions in AWS

Designing and maintaining services on AWS, with a focus on resilience and performance

Working on distributed systems that handle big data processing at scale

Building and evolving our test automation frameworks

Troubleshooting issues, working closely with colleagues

Staying up to date with the latest tools, libraries and tech approaches

Using Git Lab, Jira, and Confluence to work effectively in a modern agile setup

What you’ll bring:

Strong Python skills and experience building scalable backend services

Hands-on experience with AWS, microservice architectures, and containerised environments

Experience working on data-heavy or distributed systems

Familiarity with agile delivery and test-driven development

Self-sufficiency combined with a collaborative mindset and…