Senior Bioprocess Engineer, Downstream Processing; DSP m​/f​/d

Senior Bioprocess Engineer, Downstream Processing (DSP) 80%-100% (m/f/d)

The actual location of this job is in Visp, Switzerland
. Relocation assistance is available for eligible candidates and their families, if needed.

Join Lonza's world-class biomanufacturing site in Visp and play a critical role in delivering life-changing therapies to patients worldwide. As a Senior Bioprocess Engineer (DSP), you will provide technical leadership for downstream processing operations, combining hands-on manufacturing support with engineering expertise to ensure safe, compliant, and reliable GMP production.

This role is primarily based on site. Working together in person supports close, real-time collaboration and the technical precision needed to manufacture medicines to the highest quality and safety standards.

• An agile career and dynamic working culture within a global leader in life sciences.
• The opportunity to work on commercial and late-stage biopharmaceutical manufacturing processes that impact patients worldwide.
• An inclusive and ethical workplace built on collaboration, accountability, and continuous improvement.
• Compensation programs that recognize high performance and technical expertise.
• Opportunities to lead cross-functional initiatives, mentor colleagues, and drive operational excellence.
• A variety of benefits dependent on role and location.
• Serve as the senior technical expert for downstream processing manufacturing campaigns, ensuring safe, compliant, and reliable execution of purification operations in a GMP environment.
• Provide hands-on shop floor support during campaign preparation, execution, and close‑out activities, acting as the escalation point for complex operational challenges.
• Lead technical investigations, root cause analyses, CAPAs, change controls, and risk assessments to resolve process deviations and support manufacturing excellence.
• Analyze process performance data to identify trends and implement solutions that improve plant throughput, process robustness, equipment reliability, yields, and cycle times.
• Provide subject matter expertise in chromatography, resin management, column packing, tangential flow filtration (TFF), UF/DF operations, bulk drug substance handling, and final processing activities.
• Partner closely with Manufacturing, MSAT, Quality Assurance, Quality Control, Validation, Engineering, and Supply Chain teams to support technology transfers, process validation, and operational readiness activities.
• Drive continuous improvement initiatives and mentor junior engineers and manufacturing personnel to strengthen technical capability, operational performance, and right‑first‑time execution.

• 10+ years of experience supporting GMP downstream processing operations within commercial or late‑stage biopharmaceutical manufacturing environments, with a strong presence on the manufacturing floor.
• Proven expertise in chromatography systems, purification processes, TFF/UFDF operations, and DSP process optimization.
• Demonstrated ability to troubleshoot complex process, equipment, and operational issues and implement sustainable solutions in a GMP environment.
• Strong experience with deviation investigations, root cause analysis, CAPA management, change controls, risk assessments, and GMP documentation requirements.
• Ability to use process and operational data to drive decision‑making, performance improvements, and manufacturing excellence.
• Degree in Biotechnology, Chemical Engineering, Bioprocess Engineering, Life Sciences, or a related discipline, or equivalent industry experience.
• Excellent communication, collaboration, and stakeholder management skills, with experience leading cross‑functional…