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Lead Chemist - Pharmaceutical Development

Job in Cape Town, 7561, South Africa
Listing for: Placements24
Full Time position
Listed on 2026-10-18
Job specializations:
  • Pharmaceutical
    Pharmaceutical Science/ Research, Drug Discovery, Medicinal Chemist
Job Description & How to Apply Below
About the Role

Our client seeks a distinguished Lead Chemist to spearhead pharmaceutical development initiatives in their state-of-the-art facility in Cape Town . This senior position involves overseeing the synthesis, characterization, and formulation of novel drug candidates. You will play a crucial role in advancing drug discovery pipelines, ensuring the quality and efficacy of pharmaceutical products, and leading a team of talented chemists. The successful candidate will be a visionary leader with extensive experience in organic chemistry and drug development, committed to innovation and excellence in a highly regulated environment, contributing to the development of life-saving therapeutics.

Key Responsibilities
  • Lead the design and execution of synthetic routes for complex organic molecules.
  • Perform comprehensive characterization of synthesized compounds using advanced analytical techniques (e.g., NMR, Mass Spectrometry, HPLC).
  • Develop and optimize drug formulation strategies to enhance bioavailability and stability.
  • Manage and mentor a team of medicinal chemists and research associates.
  • Ensure compliance with all relevant regulatory guidelines and safety protocols.
  • Collaborate with pharmacologists and toxicologists to assess drug candidates.
Requirements
  • Ph.D. in Organic Chemistry, Medicinal Chemistry, or a closely related field.
  • 10+ years of progressive experience in pharmaceutical research and development.
  • Extensive knowledge of synthetic organic chemistry and reaction mechanisms.
  • Proficiency in modern analytical and spectroscopic techniques for compound characterization.
  • Demonstrated leadership experience and ability to manage R&D projects.
  • Strong understanding of drug development processes and regulatory requirements.
Benefits
  • Highly competitive salary package with annual bonus potential.
  • Comprehensive health, life, and disability insurance.
  • Generous pension fund contributions.
  • Extensive opportunities for career advancement and specialized training.
  • Access to advanced research infrastructure and collaborative environment.
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