Senior Medical Science Liaison, Oncology

We have two Senior Medical Science Liaison (Sr. MSL) positions. One for the East and onefor the West. The MSL role is a field-based scientific expert responsible for establishing and advancing Tyra Biosciences’ medical presence in oncology, with a focus on urologic malignancies. This role will serve as a primary scientific interface between Tyra and the oncology/urology community, supporting clinical development, data generation, and pre-commercial readiness for dabogratinib and future pipeline programs.

This position requires a high degree of scientific expertise, autonomy, and executional focus, with direct investigator engagement, Key Opinion Leader (KOL) engagement, clinical trial support, and insights generation in a growing biotech environment. The Sr. MSL will serve as a key scientific partner to internal teams and external healthcare professionals.

Must have industry oncology experience as an Medical Science Liaison.

• Lead and drive clinical trial and investigator support
• Proactively engage investigators and research staff in scientific discussions related to ongoing clinical trials, driving awareness and visibility of oncology programs
• Identify, develop, and maintain peer-to-peer scientific relationships with Key Opinion Leaders (KOLs) and healthcare professionals
• Collect, synthesize, and communicate actionable field insights to internal teams
• Identify emerging trends, competitive dynamics, and evolving standards of care in genitourinary oncology/urology
• Support scientific data dissemination and medical education initiatives
• Execute the scientific engagement plan
• Support Tyra’s presence at major oncology and urology congresses
• Maintain a high level of scientific expertise in oncology and urology
• Effectively collaborate with medical affairs, clinical development, clinical operations, and other cross-functional partners, ensuring alignment across programs
• Conduct all activities in accordance with regulations and company SOPs
• Facilitate problem-solving and conflict resolution with internal and external stakeholders to reduce issues / remove roadblocks and keep teams on track with key deliverables
• Proactively work with cross-functional teams to develop, progress, and accelerate program goals
• Serve as a role model within and outside of Medical Affairs in problem identification, cross functional collaboration, and implementation of planned resolutions

• Advanced scientific degree required: MD, PharmD, or PhD
• Minimum 5+ years of MSL experience in oncology or urology (preferred) in the biotechnology or pharmaceutical industry, independently managing a large geographic territory
• Strong track record of supporting clinical trials in a late-stage or pre-commercial setting
• Late-stage oncology drug development (Phase
  3) experience required, experience in bladder cancer a plus
• Proven track record of effectively networking and building new relationships
• Excellent communication and presentation skills
• Demonstrated success in advancing drug candidates to development
• Ability to provide technical advice and assist with problem resolution
• Prior experience working in a small, start-up biotech work environment preferred
• Strong analytical and strategic ability
• Ability to work independently and to multi-task
• Ability to change pace and tasks as needed and to work in a fast-paced environment
• Proficient in MS Outlook/Word/Excel/Power Point
• Must be able to travel extensively (~60-70%), primarily in the U.S. but also internationally as needed

Base Salary Range: $238,467 - $250,800 USD

Individual compensation will be determined based on factors such as work location, skills, education, training, and experience.

• Competitive base,…