Manager Analytical Development

We are currently seeking an experienced Group Leader, Analytical Development to provide technical leadership across a portfolio of monoclonal antibody (mAb) programmes for a fast-growing biosimilars organisation in London.

This is a high-impact role focused on biosimilarity assessment, analytical strategy, and advanced molecule characterisation, working closely with cross-functional teams to support development and regulatory activities. The position offers significant visibility and the opportunity to help shape scientific capability within a growing R&D environment.

Please note, this position is 5 days on-site (non-negotiable). Visa sponsorship may be available for exceptional candidates based in the EU.

Key Responsibilities

• Lead analytical development activities for biosimilar mAb programmes.
• Drive biosimilarity and analytical similarity assessment strategies.
• Provide technical oversight of HPLC methods including CEX, SEC, Glycan, HIC and Protein
  
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• Interpret LC-MS and advanced characterisation data.
• Support capillary electrophoresis techniques including cIEF and CE-SDS.
• Contribute to regulatory submissions and CMC documentation.
• Act as a subject matter expert in cross-functional project reviews.
• Mentor and develop analytical scientists.
• Identify and implement innovative analytical technologies and approaches.

Requirements

• Strong experience in analytical development of biologics or biosimilars, ideally monoclonal antibodies.
• Expertise in analytical similarity assessment and molecule characterisation.
• Hands-on knowledge of HPLC platforms, CE techniques and mass spectrometry data interpretation.
• Experience supporting regulatory submissions and analytical CMC documentation.
• Proven ability to provide technical leadership and mentor scientific teams.
• Strong understanding of PTMs, impurity profiling and analytical method development.