Metabolomic Scientist Job Central London area,City Of London England UK,Research/Development

Location: City Of London

Metabolomics Scientist (LMS 2416)

Salary: £42,159 plus London Allowance £5,560 per annum

Fixed term until 31 March 2028 | Full time |

Location:

Hammersmith, London

Closing date 18 June 2026

Overall purpose:

The Laboratory of Medical Sciences (LMS) at Hammersmith Hospital is a core‑funded MRC research institute and enjoys close links with its partners at Imperial College and at the Imperial College Healthcare NHS Trust. The LMS's research focuses on strengthening the basic science underpinning our understanding of human diseases and the translation of such high‑quality research into a clinical setting. Within the LMS, the Metabolomics facility focuses on advanced collaborative requirements in metabolomics and lipidomics.

The facility is actively expanding its high‑resolution technology base through the onboarding of next‑generation Orbitrap architectures and upcoming Tribid installations.

The post holder will act as a core Metabolomics specialist within the facility, taking independent technical ownership of high‑end mass spectrometry platforms. They will work closely with researchers, taking the scientific lead on the metabolomics side of collaborative projects, ranging from experimental design through to final publication, both internally and with external collaborators.

Main duties / key responsibilities:

To lead the development of validation of metabolomics mass spectrometry based‑workflows, with a focus on high‑resolution platforms.
To take the scientific and technical lead on the metabolomics component of collaborative projects.
To operate and maintain liquid chromatography‑mass spectrometry (LC‑MS) systems (Thermo Orbitrap Excedion Pro, IQ-X, Waters TQ‑XS).
To establish, track, and review rigorous Quality Assurance (QA) and Quality Control (QC) metrics to ensure data accuracy and instrument stability.
To perform advanced hardware troubleshooting and coordinate directly with service engineers.
To train and work collaboratively with team members as well as researchers in MRC LMS research groups.
To disseminate skills and expertise by assisting collaborators with experimental design, sample extraction protocols, and data interpretation.
To develop and apply computational pipelines for complex data analysis (targeted and untargeted) and data visualization.
To contribute to peer‑reviewed publications and maintain accurate, complete records of analysis projects and methods.
To present and communicate methods and results at facility meetings, workshops, and seminars.
To oversee facility consumables infrastructure and track system utilization metrics.
To comply with LMS safety practices and deliver safety training when appropriate.

Other Duties

To undertake appropriate administration tasks.
To attend relevant meetings.
To undertake any necessary training and/or professional development.

Any other duties commensurate with the grade of the post as directed by the supervisor.

Corporate/Local responsibilities & requirements

The job holder must at all times carry out their responsibilities with due regard to the MRC’s:

Code of Conduct
Equality and Diversity policy
Health and Safety policy
Data Protection and Security policy

Person requirements Education / Qualifications / Training required:

PhD in Analytical Sciences, Chemistry, Biochemistry or a related discipline or alternatively, equivalent professional experience

Knowledge and experience:

Hands‑on experience with LC‑MS and development of metabolomics workflows on high‑resolution platforms (such as Thermo Orbitrap Excedion Pro/IQ‑X).
Hands‑on experience with LC‑triple quadrupole (such as Waters TQ‑XS).
Proficiency in the acquisition and processing of metabolomics data including the implementation of rigorous data QA and QC tracking.
Ability to take the technical and scientific lead on the metabolomics component of collaborative research projects.
Experience of working with biological and biomedical scientists in a collaborative fashion from experimental design to data interpretation.
Previous experience of working with biological and clinical samples.
Ability to communicate well, train scientists and disseminate skills and expertise.
Track record of contribution to peer reviewed…