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Global Site Activation Manager

Job in Centurion, 0014, South Africa
Listing for: IQVIA
Full Time position
Listed on 2026-10-17
Job specializations:
  • Business
    Regulatory Compliance Specialist
Job Description & How to Apply Below
Site Activation Manager, Global Study Leadership

At IQVIA, our Site Activation Managers play a critical role in bringing new therapies to patients faster. As part of the Global Study Leadership team, you'll lead site activation activities across global clinical trials, working with sponsors, sites and cross-functional teams to drive study start-up success. It's an opportunity to make a global impact while advancing your career in clinical research leadership.

Why Join Global Study Leadership?

Global Study Leadership is a global, full-service team delivering clinical trials through both therapeutically aligned and customer-dedicated delivery units. You'll work across diverse therapeutic areas and partner with leading pharmaceutical and biotechnology companies, gaining exposure to a broad range of studies, countries, regulatory environments and delivery models. With structured career development, tailored training, mentorship and opportunities to grow across Site Activation, Clinical, Project Management, and Oversight roles, you'll build expertise that accelerates your career.

Supported by a collaborative culture, flexible working environment and AI-enabled technologies, you'll help drive efficient study delivery while bringing new treatments to patients worldwide.

What You'll Be Doing

You'll lead study start-up activities across global, regional, and country-level programs, ensuring studies are activated efficiently, compliantly, and on schedule. Working as part of an integrated cross-functional team, you'll partner with sponsors, sites, and stakeholders worldwide to accelerate patient enrolment and drive successful clinical trial delivery.

Key Responsibilities
  • Leading site identification, feasibility, regulatory submissions, ethics approvals and site contracting
  • Developing and executing Site Activation Management Plans aligned to study strategy and objectives
  • Performing protocol amendments
  • Driving study start-up timelines and critical milestones
  • Managing regulatory strategies, approvals and essential study documentation
  • Negotiating contracts and regulatory documents while ensuring local and global compliance
  • Identifying risks, resolving issues and implementing mitigation plans
  • Building strong relationships with sponsors, sites, and cross-functional stakeholders
  • Monitoring project metrics, budgets, timelines and performance indicators
  • Providing project updates, reports, presentations and operational insights
  • Supporting proposal development, bid defence activities and customer engagement
  • Mentoring colleagues and contributing to continuous improvement initiatives
What We're Looking For
  • Bachelor's degree in Life Sciences or a related field
  • Experience in site activation, study start-up, protocol amendments, regulatory affairs or clinical operations
  • Strong knowledge of ICH-GCP, clinical trial regulations, ethics processes and regulatory requirements
  • Experience managing timelines, budgets, risks and cross-functional stakeholders
  • Strong communication, negotiation and stakeholder management skills
  • Ability to lead complex projects and drive outcomes in a global environment
  • Strong planning, organizational and problem-solving skills
  • Experience working across cultures and geographies
  • Passion for innovation and leveraging technology to improve clinical trial delivery
Build Your Future with IQVIA

IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide. Learn more at

IQVIA is committed to integrity in our hiring process and maintains a zero tolerance policy for candidate fraud. All information and credentials submitted in your application must be truthful and complete. Any false statements, misrepresentations, or material omissions during the recruitment process will result in immediate disqualification of your application, or termination of employment if discovered later, in accordance with applicable law.

We appreciate your honesty and professionalism.

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