Principal Chemist - Analytical Development

About the Role

Our client is actively seeking a highly experienced Principal Chemist specializing in Analytical Development to join their prestigious research and development facility in Centurion . This senior role is critical for designing, validating, and implementing sophisticated analytical methods for the characterization of new chemical entities and pharmaceutical products. You will play a key role in ensuring the quality and integrity of our client's innovative pipeline, collaborating with formulation scientists, process chemists, and regulatory affairs.

This position demands a deep understanding of analytical chemistry principles and a commitment to excellence in a highly regulated environment.

• Lead the development, optimization, and validation of analytical methods for small molecules and biologics using techniques such as HPLC, GC, MS, and spectroscopy.
• Investigate and troubleshoot complex analytical challenges, ensuring timely resolution and robust method performance.
• Author and review method validation reports, analytical procedures, and regulatory submission documents.
• Provide expert analytical support to drug discovery, process development, and quality control teams.
• Mentor and guide junior analytical chemists, fostering technical expertise and best practices within the team.
• Stay current with emerging analytical technologies and regulatory guidelines, recommending implementation where appropriate.

• Ph.D. in Chemistry, Analytical Chemistry, Pharmaceutical Sciences, or a related discipline.
• Minimum of 8 years of progressive experience in analytical development within the pharmaceutical or chemical industry.
• Extensive hands-on experience with a wide range of analytical instrumentation and methodologies.
• Strong knowledge of ICH guidelines and regulatory requirements for analytical validation.
• Demonstrated ability to lead complex projects, manage timelines, and effectively communicate scientific findings.
• Proven experience in troubleshooting and problem-solving for analytical methods.

• Exceptional salary and comprehensive benefits package, including advanced health coverage.
• Significant opportunities for professional growth and leadership development.
• Access to cutting-edge analytical instrumentation and collaborative research projects.
• Relocation assistance may be available for highly qualified candidates.
• A culture that values scientific rigor, innovation, and employee well-being.