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Senior Research Chemist - Organic Synthesis

Job in Centurion, 0014, South Africa
Listing for: Placements24
Full Time position
Listed on 2026-09-06
Job specializations:
  • Research/Development
    Drug Discovery, Research Scientist, Pharmaceutical Science/ Research, Biotechnology
  • Science
    Drug Discovery, Research Scientist, Pharmaceutical Science/ Research, Biotechnology
Job Description & How to Apply Below

About the Role

Our client is seeking a talented Senior Research Chemist specializing in Organic Synthesis to join their advanced chemical research and development facility in Centurion . This role is crucial for designing and executing synthetic routes for novel compounds, intermediates, and active pharmaceutical ingredients (APIs). You will work in a state-of-the-art laboratory environment, collaborating with a team of chemists and scientists to drive innovation in chemical discovery.

The ideal candidate has a deep understanding of synthetic organic chemistry, a passion for problem-solving, and a commitment to producing high-quality research.

Key Responsibilities
  • Design and execute multi-step synthetic routes for complex organic molecules.
  • Optimize reaction conditions to improve yield, purity, and efficiency.
  • Characterize synthesized compounds using advanced analytical techniques (NMR, MS, HPLC, etc.).
  • Troubleshoot challenging synthetic problems and develop creative solutions.
  • Collaborate with analytical and process chemistry teams to ensure smooth scale-up.
  • Maintain detailed laboratory notebooks and prepare technical reports.
Requirements
  • Ph.D. in Organic Chemistry or a closely related field.
  • 5-7 years of hands-on experience in synthetic organic chemistry, preferably in a research or drug discovery setting.
  • Proven expertise in a wide range of organic reactions and synthetic methodologies.
  • Proficiency with modern spectroscopic and chromatographic analytical techniques .
  • Strong understanding of reaction mechanisms and kinetics.
  • Excellent problem-solving skills and the ability to work effectively in a team environment.
Benefits
  • A competitive salary package commensurate with experience.
  • Comprehensive medical, dental, and vision insurance coverage.
  • Significant opportunities for professional growth and continuing education.
  • Access to cutting-edge laboratory equipment and resources in Centurion .
  • A dynamic and collaborative research culture focused on scientific advancement.
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Position Requirements
10+ Years work experience
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