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Senior Scientist - Drug Discovery

Job in Centurion, 0014, South Africa
Listing for: Placements24
Full Time position
Listed on 2026-09-28
Job specializations:
  • Research/Development
    Drug Discovery, Pharmaceutical Science/ Research, Research Scientist
  • Pharmaceutical
    Drug Discovery, Pharmaceutical Science/ Research
Job Description & How to Apply Below

About the Role

Our client is actively seeking a highly accomplished Senior Scientist to spearhead their Drug Discovery initiatives in Centurion . This leadership role involves directing research efforts to identify and validate novel therapeutic targets and to develop small molecule or biologic drug candidates. You will work within a multidisciplinary team, utilizing state-of-the-art technologies to accelerate the drug development pipeline. The position demands a strategic thinker with a proven track record in medicinal chemistry, pharmacology, or a closely related discipline, committed to bringing innovative medicines to patients.

Key Responsibilities
  • Lead the design and execution of discovery research programs aimed at identifying and optimizing novel drug candidates.
  • Manage and mentor a team of scientists and research associates involved in various stages of drug discovery.
  • Develop and implement robust assays for target validation, compound screening, and lead optimization.
  • Collaborate closely with external partners and academic institutions to leverage external expertise and technologies.
  • Analyze and interpret complex experimental data, making critical decisions to advance or terminate projects.
  • Ensure compliance with all relevant regulatory guidelines and company policies in the research conducted in Centurion .
Requirements
  • Ph.D. in Pharmacology, Medicinal Chemistry, Biochemistry, or a relevant field.
  • A minimum of 7 years of progressive experience in the pharmaceutical or biotechnology industry, with a focus on drug discovery .
  • Demonstrated success in leading discovery projects from target identification through to lead candidate selection.
  • Strong understanding of pharmacology , pharmacokinetics , and drug metabolism principles.
  • Experience with high-throughput screening (HTS) and structure-activity relationship (SAR) studies.
  • Exceptional leadership, communication, and project management skills.
Benefits
  • Highly competitive salary and performance-based bonus structure.
  • Comprehensive benefits package including health, dental, and life insurance.
  • Relocation assistance may be available for exceptional candidates.
  • Significant opportunities for career advancement and leadership development.
  • Access to cutting-edge drug discovery platforms and collaborative research environment.
  • A forward-thinking company culture dedicated to scientific innovation in Centurion .
Position Requirements
10+ Years work experience
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