Research Specialist

Under supervision of the Principal Investigator, this position will be tasked with performing both lab managerial and advanced cellular and molecular biology experiments to support research projects investigating the genetic variants associated with psychiatric and neurodegenerative disorders. Lab managerial duties include ordering, receiving, and documenting reagents, supplies, and equipment; ensuring that the lab complies with mandated safety protocols; disposal of chemical and biohazard waste;

and maintaining equipment in good working condition. Cellular and molecular biology experiments include fluorescence-activated cell sorting and high-throughput genomic library generation. This will require generating massively parallel reporter assay (MPRA), perturb-seq, RNA-seq, and DNA-seq libraries; generating viral plasmids that can transduce human neural cells and mouse tissues; performing multiplexed reporter assays; performing PCR and gel electrophoresis; primary neuronal cell culture and transduction;

mouse colony maintenance and tissue harvest, preparing buffers, solutions, and chemicals for lab experiments; data analysis and interpretation; maintaining database of experimental results; assisting with grant applications and publications; providing technical assistance in the lab, including assisting other members of the lab; and assisting with training of lab assistants and students.

The University of North Carolina at Chapel Hill is a public research university in Chapel Hill, North Carolina.

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