UNIV - Post Doctoral Scholar - Pediatrics: DCRI

The Department of Pediatrics, Darby Children’s Research Institute’s Laboratory of Dr. Haemmerich is seeking a Post-doctoral to assist ongoing research efforts to develop targeted chemotherapy delivery for cancer treatment.

Medical University of South Carolina (MUSC - Univ)

Employee

Regular

CC001013 COM PEDS Children's Research Institute CC

Hourly, Salary

University-00

0.00 - 0.00 - 0.000

20

Specifically, the job duties will include producing liposomal drug carriers, studies in rodent cancer models, imaging (MRI, fluorescence imaging), and computer modeling. The fellow will be expected to handle rodents and may assist in catheter implantation procedures.

A doctoral degree (PhD or MD/PhD) in a discipline related to biology, bioengineering or biomedicine.

• 25% Perform and/or assist in therapeutic rodent studies. This includes the intravenous administration of liposomal chemotherapy, blood sampling and animal imaging.
• 25% Assist and/or perform computer modeling studies, where tumor drug delivery is simulated.
• 10% Produce and characterize liposomal drug carriers. This includes formulating the liposomes, measuring release characteristics, and size.
• 10% Preparation and maintenance of primary cancer cell cultures. This includes standard cell culture methods, and in some cases cell viability analyses in combination with in vitro efficacy studies.
• 10% Perform routine laboratory experiments, review and analysis of data, and preparation of protocols and reports.
• 10% Maintain, clear, complete and up-to-date lab notebook and documentation of all experiments, results and reports. This may include organization of results in spreadsheets and other documents.
• 5% Processing and analysis of tissues such as rodent tumors. This includes the quantification of tumor drug uptake with established methods such as by fluorometry and/or high-performance liquid chromatography (HPLC).
• 5% Assist in animal surgeries. This may include surgical removal of tumors, and implantation of vascular catheters.

Physical Requirements:

(

Note:

The following descriptions are applicable to this section: Continuous - 6-8 hours per shift; Frequent - 2-6 hours per shift; Infrequent - 0-2 hours per shift) Ability to perform job functions in an upright position. (Continuous) Ability to perform job functions in a seated position. (Continuous) Ability to perform job functions while walking/mobile. (Frequent) Ability to climb stairs. (Infrequent) Ability to work indoors.

(Continuous) Ability to work in all cold temperature extremes, i.e. spot coolers. (Frequent) Ability to bend at the waist. (Frequent) Ability to twist at the waist. (Frequent) Ability to perform ’pinching’ operations. (Continuous) Ability to fully use both hands/arms. (Continuous) Ability to perform repetitive motions with hands/wrists/elbows and shoulders. (Continuous) Ability to fully use both legs. (Continuous) Ability to reach in all directions.

(Continuous) Possess good finger dexterity. (Continuous) Ability to maintain tactile sensory functions. (Continuous) Ability to maintain good olfactory sensory function. (Continuous) Ability to lift and carry 15 lbs., unassisted. (Frequent) Ability to lift objects, up to 15 lbs., from floor level to height of 72 inches, unassisted. (Frequent) Ability to lower objects, up to 15 lbs., from height of 72 inches to floor level, unassisted.

(Frequent) Ability to push/pull objects, up to 15 lbs., unassisted. (Infrequent) Ability to lift and carry objects up to 15 lbs. a distance of five (5) floors and to outlying buildings. (Frequent) Ability…