Bioinformatics Analyst

Bioinformatics Analyst

At Cincinnati Children’s Hospital Medical Center, we are committed to advancing precision medicine and delivering timely, accurate genetic and genomic insights that directly impact patient care. As the Genetic and Genomic Diagnostic Laboratory (GGDL) expands, we need a Bioinformatics Analyst to support our most complex and high‑revenue genetic and genomic tests.

Job Responsibilities

• Execute and monitor data analysis pipelines (sequence alignment, variant calling, sample identity) for laboratory generated data (NGS, microarray).
• Work with laboratory and clinical teams to verify results meet SOPs and turnaround time requirements.
• Monitor bioinformatics work queues to ensure timely case processing.
• Identify and resolve testing discrepancies and handle urgent clinical laboratory requests.
• Support quality control of laboratory generated data and ensure accuracy and completeness.
• Ensure data are securely stored yet highly accessible to authorized users.

Analysis Pipeline & Workflow Management

• Maintain and troubleshoot existing bioinformatics workflows.
• Contribute to laboratory documentation (test validation reports, change logs) to meet clinical regulatory standards.
• Maintain accurate records of analyses, software versions, and databases.
• Contribute to the evaluation and development of new software solutions to support lab testing and improve workflow performance.

Software Evaluation & Tool Development

• Support development, validation, and deployment of analysis pipelines for new clinical lab tests.
• Develop new applications as clinical testing modules for in‑house Laboratory Management System.
• Manage projects and timelines, utilizing version control and strict deployment guidelines.

Collaboration And Communication

• Interface with laboratory and clinical teams to define requirements.
• Work closely with other teams (e.g., IT) for data analysis issues.
• Communicate with third‑party software and platform companies to ensure workflow updates and bug fixes.

Publication

• Contribute to analysis reports and figures for publications.

Job Qualifications

• Bachelor’s degree in a related field required.
• 0+ years of experience in a related discipline (entry‑level applicants encouraged).

Preferred Qualifications

• BS or MS in Bioinformatics, Computational Biology, Biomedical Informatics, Data Science, Systems Biology, or related field.
• Proficiency in Linux/Unix command line and scripting languages (Python, Bash, or R); experience with HPC clusters and version control platforms.
• Hands‑on experience analyzing NGS and microarray data; familiarity with tools such as DRAGEN, BWA, GATK, samtools, IGV, Manta.
• Experience with database design, SQL, and bioinformatics databases such as Clin Var, Clin Gene, gnom
  
  AD and OMIM.
• Familiarity with clinical lab testing workflows, CAP‑certified environments, molecular diagnostic processes.
• Experience with workflow management systems (Nextflow, Snakemake), containerization, web development (PHP, JavaScript/jQuery/AJAX), data integration using Mirth Connect.
• Experience applying cloud computing and machine learning techniques to biomedical data.

Location

• Kasota - 3244 Burnet

Schedule

• Full time
• Day (United States)

Benefits

• Medical coverage starting day one.
• Competitive retirement plans.
• Tuition reimbursement.
• Employee discount programs.
• Shift and weekend differential pay for qualified positions.
• Employee Resource Groups support.
• Health wellness programs.
• Relocation assistance (qualified positions).

About Cincinnati Children’s

We come to work with one goal: to make children’s health better. We believe in a holistic team approach, both in caring for patients and their families, and in advancing science and discovery. We strive to do better and find energy and inspiration in our shared purpose.

Comprehensive

Job Description Provided Upon Request. EEO Statement

Cincinnati Children’s is proud to be an Equal Opportunity Employer committed to creating an environment of dignity and respect for all our employees, patients, and families. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, genetic information, national origin, sexual orientation, gender identity, disability or protected veteran status. EEO/Veteran/Disability.

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