Senior Director, Program Manager

Join Abeona Therapeutics as a Senior Director, Program Manager in our Program Leadership department and help advance a mission-driven portfolio of cell and gene therapies. In this role, you will lead cross-functional development programs, translate strategy into integrated execution plans, and influence portfolio-level decisions. You will collaborate with colleagues across the organization who are committed to developing innovative therapies for patients.

This is a U.S.

-based remote role supporting colleagues across the country. Abeona's manufacturing facilities are in Cleveland, Ohio.

Current projects are focused primarily on preclinical and IND-enabling programs, with responsibilities expected to span the full development lifecycle.

Join us in making cure the new standard of care. At Abeona Therapeutics, we exist for our patients and their caregivers; their needs guide our decision-making. We challenge ourselves to think differently, move quickly, and deliver solutions. We hold ourselves to the highest ethical and quality standards. We persevere with resilience and focus to achieve our mission. We build trust through humility, mutual appreciation, openness, and respect.

Reporting to the VP, Program Leadership, the Senior Director, Program Manager provides strategic leadership for one or more programs within Abeona's portfolio and directs integrated, cross-functional program planning and execution. The role partners with program and functional leaders to align strategy, timelines, resources, risks, and decisions in support of program and corporate goals.

This is an individual-contributor leadership role with responsibility for influencing cross-functional teams, strengthening program-management practices, and advancing gene therapy programs in a highly regulated environment.

This is a remote role, with core work hours from Monday to Friday between 9:00 a.m. and 5:00 p.m. (ET). Occasional work outside core hours, including early mornings, evenings, or weekends, may be required.

This position works collaboratively with colleagues across the U.S., so some flexibility is required depending on the successful candidate's location.

You are an accomplished biopharma program manager who can translate complex cell and gene therapy strategies into clear, executable plans. With deep cross-functional therapy development experience, you anticipate risks, align timelines and resources, and keep high-priority programs moving toward corporate and patient-focused goals.

You build credibility with executives and functional leaders through concise communication, sound judgment, and productive accountability, while creating the tools, metrics, and decision frameworks teams need to succeed. You also bring a collaborative, improvement-oriented leadership style and are motivated to mentor others and strengthen program management capabilities across the organization.

• Provides strategic leadership for one or more portfolio programs and guides major program decisions.
• Develops and maintains integrated program strategies, critical paths, and cross-functional milestones.
• Ensures alignment among program strategy, functional plans, corporate priorities, and governance decisions.
• Establishes governance, directs critical work streams, and ensures appropriate Program Leadership coverage.
• Leads one or more programs within the overall portfolio.
• Manages and tracks the overall timeline for the program, including…