Senior Director, Global Program Management Oncology

Senior Director, Global Program Management Oncology

Join to apply for the Senior Director, Global Program Management Oncology role at GSK
.

Location:

Upper Providence, PA;
Boston, MA.

Posted:
Dec 18 2025

Business Introduction

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines, combining our understanding of the immune system with cutting‑edge technology to transform people’s lives. GSK fosters a culture ambitious for patients, accountable for impact, and committed to doing the right thing, making sure that we focus our efforts on accelerating significant assets that meet patients’ needs and have the highest probability of success.

We’re uniting science, technology, and talent to get ahead of disease together.

Position Summary

As the Senior Director of Program Management Oncology for a flagship oncology asset, you will be the driving force behind flawless execution—translating strategy into action and ensuring disciplined delivery of program milestones. You will shape critical decisions by influencing stakeholders through data‑driven insights and external perspectives, while fostering a culture of accountability and agility. Your role demands operational rigor, proactive risk management, and the ability to challenge assumptions to accelerate progress without compromising quality or safety.

• Act as the Medicine Development Leader’s strategic partner and primary point of contact for the program’s Medicine Development Team (MDT).
• Oversee a complex, multi‑tumor program—integrating clinical development, asset and evidence strategies into a unified vision.
• Lead all project management aspects of this high‑visibility initiative, ensuring milestone delivery at pace while upholding quality and safety.
• Integrate clinical, regulatory, CMC, and commercial strategies into a unified program plan; guide strategic discussions and encourage diverse viewpoints to reach actionable outcomes.
• Engage in critical thinking: question assumptions, explore new approaches, simplifying complex topics into actionable insights for senior leaders.
• Promote agility and execution excellence: lead scenario planning, minimize disruption, communicate changes clearly.
• Own program execution, proactively resolve challenges, lead planning and risk management, track progress, identify opportunities for innovation and efficiency, accelerate outcomes by streamlining decision‑making and removing obstacles.
• Engage senior leaders, governance bodies, external partners, and subject matter experts; lead tailored meetings, cultivate trusted relationships, influence through credibility, data‑driven insights, and composure.
• Facilitate governance interactions; translate complexity into clear, data‑driven recommendations; summarize strategy, risks, options.
• Demonstrate leadership & team development: mentor project managers, foster ownership, high standards, and calm, confident leadership to handle ambiguity.

• MS, MBA in Life Sciences or related field.
• Experience working on an oncology asset.
• 10+ years of oncology drug development in matrix teams, including pharmaceutical consulting.
• Experienced in project management using PM principles (e.g., PMI/PMBOK), including risk management, planning, execution, scenario analysis, communication, and reporting.
• Experience maintaining project plans, budgets, forecasts, and documentation in Planisware.

• 10+ years in drug development, with at least 5 years in oncology program or portfolio management.
• Minimum of 3 years’ experience in life sciences consulting, specializing in strategic planning and project delivery within the pharmaceutical sector.
• Proven track record leading large, cross‑functional oncology programs (multi‑asset or multi‑region).
• Advanced program management tools (Planisware, MS Project, Smartsheet), risk modeling, budget/resource tracking.
• Soft skills:
  
  executive presence, stakeholder influence, strategic communication, ability to navigate ambiguity.
• Skilled in leading project team meetings.
• Proficient in preparing for…