Tenured And Tenure-Track Faculty Positions

Build an ambitious genetics and genomics program in one of the field’s most integrated research environments.

The Department of Molecular and Human Genetics at Baylor College of Medicine invites applications from creative, collaborative investigators whose work will define the next generation of genetic discovery and its translation to human health. We welcome applications at the Assistant, Associate, or Full Professor level from established leaders and rising investigators in computational, experimental, or genuinely cross-disciplinary research.

We seek Ph.D.

- and/or M.D.

-trained scientists with a record of rigorous, high-impact scholarship and the potential to sustain an externally funded research program. Successful candidates will establish an independent program, contribute to a highly collaborative scientific community, and participate in the education and mentorship of trainees. Research may address rare or common disease, fundamental genetic and genomic mechanisms, technology development, or other major questions in biology and medicine.

• Artificial intelligence, machine learning, statistical genetics, algorithm development, and responsible genomic data science
• Advanced analysis of whole-genome, long-read, single-cell, spatial, multi-omic, proteomic, imaging, biobank, and electronic health record data
• Variant interpretation; genotype–phenotype relationships; population, comparative, structural, functional, and evolutionary genomics
• Knowledge representation, causal and network modeling, data integration, visualization, and scalable software or cloud-enabled systems

• Genetic, epigenetic, nucleomic, RNA, protein, metabolic, cellular, developmental, or systems mechanisms in health and disease
• Human genetics integrated with model organisms, organoids, patient-derived systems, iPSCs, transdifferentiated cells, and other innovative platforms
• Functional genomics, single-cell and spatial biology, genome and epigenome engineering, synthetic biology, quantitative phenotyping, and technology development
• Mechanism-driven therapeutic discovery, including gene, RNA, cell, small-molecule, and other precision approaches

• Sustained national leadership in genetics research, with the Department reporting the highest number of NIH grants among genetics departments at U.S. medical schools and average annual NIH funding approaching $75 million over the past decade.
• More than 70 primary research faculty spanning computational genetics, bioinformatics, functional genomics, genome structure and function, disease mechanisms, model systems, and therapeutic development.
• A deeply integrated ecosystem linking fundamental discovery, the Human Genome Sequencing Center, Baylor Genetics, the Medical Genetics Multiomics Laboratory, the Undiagnosed Diseases Center, major disease-focused centers, and one of the country’s largest clinical genetics programs.
• Access to exceptional collaborators and trainees across Baylor, Texas Children’s Hospital, the Jan and Dan Duncan Neurological Research Institute, the Dan L Duncan Comprehensive Cancer Center, Rice University, UTHealth Houston, MD Anderson Cancer Center, the University of Houston, and the broader Texas Medical Center.

The Department brings physicians, experimental scientists, quantitative researchers, clinical laboratories, and trainees into a shared genetics and genomics mission. Its research programs span genome sequencing and interpretation, computational and integrative biomedicine, model-organism and precision disease modeling,…