Postdoctoral Scholar Position in RNA Nanotechnology

Organization: The Ohio State University Department: Pharmacy – Pharmaceutics and Pharmacology Laboratory: Interdisciplinary Lab of Dr. Peixuan Guo Location: Columbus, Ohio, United States Position: Post Doctoral Scholar – RNA Nanotechnology Job Requisition : R158456

The Ohio State University is seeking PhD scientists to join the interdisciplinary laboratory of Dr. Peixuan Guo, working at the interface of biophysics, RNA biology, nanotechnology, molecular biology and therapeutic development. The research programme encompasses RNA–protein interactions, RNA structure and function, RNA nanotechnology, RNA dynamics and motility, RNA therapeutics, nucleic acid chemistry, RNA delivery and computational approaches to protein and RNA structure.

The postdoctoral scholar will apply modern technologies to chemically modify RNA nanoparticles or messenger RNA (mRNA) for in vivo imaging and develop approaches for delivering RNA in vivo for disease treatment and cancer prevention. The laboratory aims to train the next generation of scientific leaders and develop research capabilities that can translate advances in RNA nanotechnology into biomedical applications and therapeutics.

• RNA–protein interactions.
• RNA-based ATP binding and ATP hydrolysis.
• RNA nanotechnology.
• RNA structure and function.
• RNA dynamics and motility.
• RNA therapeutics.
• Nucleic acid chemistry.
• Cancer mRNA vaccines.
• RNA delivery.
• Regulation of proteins by noncoding RNA.
• Molecular biology and biotechnology.
• Biochemistry.
• Protein and RNA structural computation.
• TIRF imaging.
• Optical tweezers.
• In vivo RNA imaging and delivery.

• Conduct postdoctoral research in RNA nanotechnology and related interdisciplinary areas.
• Investigate RNA structure, dynamics, function and interactions with proteins.
• Apply modern technologies to RNA nanoparticles and mRNA.
• Chemically modify RNA nanoparticles or mRNA for biomedical and imaging applications.
• Investigate approaches for in vivo RNA delivery.
• Contribute to research targeting disease treatment and cancer prevention.
• Apply experimental and computational methods appropriate to the research project.
• Analyse and communicate research findings through scientific publications and presentations.
• Collaborate effectively within an interdisciplinary research environment.
• Contribute to the training and development of emerging technologies in RNA nanotechnology.

• Biophysics.
• Chemistry.
• Biochemistry.
• Cell Biology.
• Molecular Biology.
• Bio-computation.
• Biomedical Engineering.

• Strong oral and written communication skills.
• Good organisational abilities.
• Effective interpersonal and teamwork skills.
• High motivation for interdisciplinary scientific research.

Previous experience in optics or imaging involving RNA or proteins is preferred. Relevant experience in RNA nanotechnology, molecular biology, nucleic acid chemistry, RNA therapeutics, RNA delivery, biophysics, imaging or computational structural biology may also be valuable for the research environment.

• Position: Post Doctoral Scholar.
• Position type: Term (Fixed Term).
• Working hours: 40 hours per week.
• Shift: First Shift.
• Location: Parks Hall (0273), Columbus Campus.
• Duration: Not specified in the vacancy.
• Start date: Not specified.
• Salary: Not specified.

Additional Information:
Final candidates are subject to successful completion of a background check. A drug screen or physical examination may be required during the post-offer process. The Ohio State University is an equal opportunity employer, including veterans and individuals with disabilities.

Not specified. The vacancy page does not provide a closing date. Applicants should refer to the official application portal for the current status of the position.

Official vacancy and application page: