Biologist - Approach Methodologies; NAMs

Battelle delivers when others can’t. We conduct research and development, manage national laboratories, design and manufacture products and deliver critical services for our clients - whether they are a multi-national corporation, a small start-up or a government agency. We recognize and appreciate the value and contributions of individuals from a wide range of backgrounds and experiences and welcome all qualified individuals to apply.

Battelle is seeking an early-career Scientist with a recent PhD and a strong interest in New Approach Methodologies (NAMs), especially complex in vitro models including microphysiological systems (MPS) and other human-relevant non-animal testing platforms. This role will contribute to the development, application, and evaluation of advanced non-animal testing platforms—including organoids, organ-on-chip systems, 3D in vitro models, and computational approaches—to support chemical safety assessment, biomedical research, and product development.

The Biologist II will work as part of multidisciplinary teams of biologists, engineers, data scientists, and regulatory specialists. The successful candidate will independently lead defined research activities, contribute scientific expertise to project teams, and build experience translating emerging human-relevant technologies into reliable, decision-ready scientific tools.

• Design, execute, analyze, and document research studies involving NAMs, MPS, organoids, organ-on-chip platforms, and other physiologically relevant in vitro models.
• Develop technical expertise in one or more areas of human-relevant toxicology, such as advanced cell culture, tissue engineering, MPS operation, mechanistic toxicology, omics, or computational toxicology.
• Support the design, implementation, optimization, and qualification of MPS platforms for defined biological, toxicological, or safety-assessment applications.
• Conduct experimental studies to evaluate model performance, reproducibility, biological relevance, and applicability to specific scientific questions.
• Generate, organize, analyze, and interpret experimental data; apply appropriate statistical methods and data-visualization approaches.
• Assist with integration of MPS data with complementary approaches, including transcriptomics, metabolomics, proteomics, computational models, and conventional in vitro or in vivo data.
• Contribute to efforts that compare human-relevant model outputs with existing reference data and support in vitro-to-in vivo extrapolation or translational interpretation.
• Prepare high-quality technical reports, study protocols, laboratory records, data packages, and client-ready project deliverables.
• Develop, improve, and follow standard operating procedures, experimental protocols, and quality-control practices.
• Conduct and summarize literature reviews related to NAMs, MPS, organ-on-chip technology, regulatory science, and emerging best practices from organizations such as FDA, EPA, NIH, and NICEATM.
• Collaborate with internal and external research partners, including scientists from government, industry, and academia.
• Contribute to scientific publications, conference abstracts, posters, and presentations; present project results to internal teams and, as experience grows, external audiences.
• Maintain a safe, organized, and compliant laboratory environment while adhering to applicable quality, safety, and documentation requirements.
• Stay current with emerging advances in NAMs, MPS, human-relevant toxicology, and regulatory acceptance of alternative test methods.

• Bachelor’s degree in related field with 2 years of experience or master’s degree in related field; or an equivalent combination of education and or experience in a…