Manager, Quality Control Operations

The Role

Joining Moderna offers the unique opportunity to be part of a pioneering team that is revolutionizing medicine through mRNA technology, with a diverse pipeline of development programs across various diseases.

As an employee, you’ll be part of a continually growing organization, working alongside exceptional colleagues and strategic partners worldwide, contributing to global health initiatives.

Moderna’s commitment to advancing the technological frontier of mRNA medicines ensures a challenging and rewarding career experience, with the potential to make a significant impact on patients’ lives worldwide.

Moderna is solidifying its footprint within our international centre for analytical excellence in Madrid, a city known for its rich scientific heritage. This facility, the largest such centre outside the United States, exemplifies our commitment to solidifying our manufacturing network and advancing our promising mRNA product portfolio. We’re looking for talents who can contribute to our innovative research and development efforts.

We are looking for a Manager, Quality Control Operations to join our Madrid-based analytical excellence center. This role is a pivotal bridge between laboratory operations and digital innovation, ensuring streamlined QC processes across sample and data management, equipment qualification, and digital systems. As an individual contributor, you will lead the QC Operations group and drive digital transformation and operational compliance across laboratory systems.

Your work will directly support the quality control of intermediates, drug substances, and drug products—ultimately contributing to the timely and accurate delivery of Moderna’s mRNA medicines. You’ll work in close partnership with QA, IT, and Automation teams to enhance system integration and right-first-time performance. With opportunities to engage in cutting-edge automation and generative AI solutions, this role offers a front-row seat in shaping the future of digitally enabled laboratories.

• Lead and coordinate QC Operations functions including sample management, data management, equipment qualification, and digital system support
• Serve as the QC Operations lead for Madrid’s laboratory systems (e.g., LIMS, Chromeleon, LabX), acting as system owner or coordinator as assigned
• Oversee activities related to QC sample management: receipt, tracking, distribution, storage, and disposal
• Ensure robust lifecycle management of laboratory instruments and documentation in compliance with GMP and ALCOA+ principles
• Manage equipment qualification programs, including protocol execution and change control
• Drive QC data integrity through accurate, complete, and timely data governance across digital systems
• Collaborate cross-functionally to implement digital tools, streamline data workflows, and improve transparency through dashboards and analytics
• Support internal and external audits, inspections, and overall laboratory readiness

• Coach and set performance expectations within QC Operations while fostering continuous improvement
• Champion the digital transformation of QC, including paperless workflows, system upgrades, and lab automation
• Collaborate with QC Chemistry, Bioassay, Microbiology, and QA for coordinated testing operations
• Support automation initiatives that improve data flow and laboratory efficiency, exploring the integration of AI tools to drive quality and operational insights
• Author, review, and approve SOPs, protocols, validation documents, and quality records
• Lead CAPA and Change Control processes and contribute to Quality Metrics reporting
• Act as a strategic partner to Digital, Engineering, and IT teams in the alignment of lab systems with business needs
• Ensure Moderna’s safety and compliance standards are met within laboratory environments

• We digitize everywhere possible using the power of code to maximize our impact on patients. This mindset is foundational to the role, which centers around digital system ownership and lab…