EPA Biology Research Aquatic Toxicity and Bioaccumulation of PFAS

U.S. Environmental Protection Agency (EPA)

EPA-OCSPP-

A research opportunity is currently available at the Environmental Protection Agency (EPA), located in Duluth, Minnesota.

The mission of EPA is to protect human health and the environment. EPA works to ensure that:
Americans have clean air, land and water;
National efforts to reduce environmental risks are based on the best available scientific information;
Federal laws protecting human health and the environment are administered and enforced fairly, effectively and as Congress intended;
Environmental stewardship is integral to U.S. policies concerning natural resources, human health, economic growth, energy, transportation, agriculture, industry, and international trade, and these factors are similarly considered in establishing environmental policy;
All parts of society have access to accurate information sufficient to effectively participate in managing human health and environmental risks;
Contaminated lands and toxic sites are cleaned up; and chemicals in the marketplace are reviewed for safety.

Per- and polyfluoralkyl substances (PFAS) are synthetic contaminants found ubiquitously in the environment due to their broad commercial uses and chemical properties that resist degredation. While some PFAS like PFOA (perfluorooctanoic acid) and PFOS (perfluorooctane sulfonate) have received considerable attention in environmental and toxicological research, large data gaps remain. Within the past two and a half decades thousands of new PFAS have been identified, and most have little to no information on their ecological effects.

Research is currently underway to test the effects of broad classes of PFAS on aquatic organisms, determine their accumulative potential, and evaluate structure-activity relationships. The overall goal of this research supports EPA OCSPP’s focus on developing predictive approaches for hazard identification and risk assessment of data-poor PFAS.

• Developing aquatic toxicity and bioaccumulation test methods
• Preparing laboratory exposure systems for use, and monitoring and maintaining proper function of equipment
• Handling experimental chemicals and preparing exposure solutions
• Organism handling and monitoring
• Preparing samples for analytical chemistry measurements
• Using advanced instrumentation (GC, HPLC, MS, MS/MS, and Orbitrap) to quantify PFAS in exposure systems, determine purity of chemical stocks, and assess uptake into biota
• Recording experimental data with methods consistent with quality assurance guidelines
• Evaluating laboratory data, employing statistical analyses, and distilling results into reports for team members, collaborators, and other interested parties.
• Presenting research findings at meetings, conferences, and workshops
• Helping with or independently preparing manuscripts for peer-reviewed publication

This opportunity will provide a solid springboard for career development or pursuing advanced education. Under the guidance of a mentor, you will gain professional skills which will provide a practical foundation for future employment in research, contract or production laboratories, or environmental regulation. You will be part of a multi-disciplinary team of scientists and will collaborate with highly regarded researchers within and outside of the EPA.

Additionally, you will have opportunities for honing public speaking and technical writing skills.

Kevin Lott (lott.kevin) and Sarah Kadlec (kadlec.sarah). If…