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Process Chemist - API Manufacturing

Job in Durban, 3611, South Africa
Listing for: Placements24
Full Time position
Listed on 2026-09-12
Job specializations:
  • Manufacturing / Production
    Chemical Manufacturing
Job Description & How to Apply Below

About the Role

Our client is seeking a skilled and innovative Process Chemist to join their dynamic Active Pharmaceutical Ingredient (API) manufacturing team in Durban . This role is critical for optimizing and scaling up chemical processes to ensure efficient, safe, and high-quality production of APIs. You will work on process development, validation, and troubleshooting, playing a key part in the journey from laboratory synthesis to commercial manufacturing.

The ideal candidate has a strong foundation in organic chemistry and chemical engineering principles, with a passion for problem-solving and continuous process improvement within a regulated pharmaceutical environment.

Key Responsibilities
  • Develop, optimize, and scale-up chemical synthesis routes for APIs, focusing on safety, efficiency, and cost-effectiveness.
  • Conduct process hazard analyses and implement necessary safety controls for chemical manufacturing operations.
  • Perform process validation studies and generate documentation required for regulatory submissions.
  • Troubleshoot manufacturing issues, identify root causes, and implement corrective and preventative actions.
  • Collaborate with analytical chemists, engineers, and production personnel to ensure seamless technology transfer and production.
  • Stay current with advancements in process chemistry and manufacturing technologies, proposing innovative solutions.
Requirements
  • M.Sc. or Ph.D. in Organic Chemistry, Process Chemistry, or Chemical Engineering.
  • Proven experience (3+ years) in process development and scale-up of chemical reactions, preferably in the pharmaceutical industry.
  • Strong understanding of organic synthesis, reaction mechanisms, and purification techniques.
  • Experience with process safety evaluations and hazard assessments.
  • Familiarity with GMP regulations and pharmaceutical manufacturing requirements.
  • Excellent problem-solving skills and the ability to work effectively in a team-oriented setting.
Benefits
  • Competitive salary commensurate with experience and qualifications.
  • Comprehensive health, dental, and vision insurance plans.
  • Pension fund and life assurance benefits.
  • Opportunities for professional development and continuing education.
  • Access to advanced manufacturing technologies and a supportive R&D environment.
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