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Senior Scientist - Drug Discovery

Job in Durban, 3611, South Africa
Listing for: Placements24
Full Time position
Listed on 2026-09-21
Job specializations:
  • Research/Development
    Research Scientist, Drug Discovery, Pharmaceutical Science/ Research
Job Description & How to Apply Below

About the Role

Our client is seeking an accomplished Senior Scientist to spearhead drug discovery initiatives within their state-of-the-art research facility in Durban . This critical role involves designing and executing innovative research programs aimed at identifying and validating novel drug targets and lead compounds. You will work within a dynamic, interdisciplinary team environment, contributing to the preclinical development of transformative therapies. This is an exceptional opportunity for a seasoned researcher to make a significant impact on the company's pipeline and shape the future of therapeutic development in a highly collaborative setting.

Key Responsibilities
  • Lead the design and execution of discovery research projects, focusing on target identification and validation.
  • Develop and optimize high-throughput screening (HTS) assays and lead optimization strategies.
  • Conduct in vitro and in vivo studies to characterize drug candidates and assess their efficacy and safety profiles.
  • Collaborate effectively with medicinal chemists, pharmacologists, and DMPK scientists.
  • Analyze and interpret complex experimental data, presenting findings and strategic recommendations to project teams and management.
  • Contribute to the preparation of research reports, regulatory submissions, and scientific publications.
Requirements
  • Ph.D. in Pharmacology, Biochemistry, Molecular Biology, or a related life science discipline.
  • A minimum of 6 years of relevant industry experience in drug discovery and development.
  • Demonstrated expertise in assay development, HTS, and lead optimization methodologies.
  • Strong understanding of disease biology, target validation, and pharmacokinetics/pharmacodynamics (PK/PD).
  • Proven ability to manage multiple research projects and mentor junior scientific staff.
  • Excellent problem-solving capabilities and strong communication skills for effective collaboration in Durban .
Benefits
  • Attractive annual salary with comprehensive performance incentives.
  • Generous health insurance coverage, including medical, dental, and vision.
  • Retirement savings plan with company contributions.
  • Access to advanced laboratory equipment and facilities.
  • Opportunities for career advancement and professional development within the organization.
Position Requirements
10+ Years work experience
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