Production Operator

Applied Pharmaceutical Innovation (API) brings life‑saving research to the real world by helping life science innovators bridge the gap between academic research and commercial product development. We are driven, compassionate, and laser focused on making a dramatic positive impact with everything we undertake.

When you join API, you are part of a rapidly growing team that is creating collaborative opportunities to commercialize Canadian life sciences discoveries, increasing the amount of commercial research and development in the country, and supporting Alberta as a key pillar in Canada’s life sciences sector.

You will be part of one of API's most important projects, the Canadian Critical Drug Initiative (CCDI). The CCDI is a project led by API in partnership with the University of Alberta. It aims to establish an integrated research, commercialization, and manufacturing cluster in the Edmonton Metropolitan Region.

One aspect of the project involves upgrading the Biotechnology Business Development Centre (BBDC) in the Edmonton Research Park. The upgrade will include GMP-certified manufacturing suites for API‑manufacturing, chemical‑physical testing, and Health Canada‑approved warehousing capacity.

The second part of the project is the Critical Medicines Production Centre (CMPC), which will be a new 83,000+ square‑foot manufacturing facility located on a 7‑acre plot of land in the center of the Edmonton Research Park. This facility is set to be Canada’s largest and best equipped of its kind. The CMPC's focus will be on producing small‑molecule product solutions, conducting sterile, aseptic fill, and finishing traditional and biologic drugs to meet drug shortages needs.

The Production Operator performs manufacturing activities for active pharmaceutical ingredient (API) production in accordance with approved batch records, standard operating procedures (SOPs), current Good Manufacturing Practices (cGMP), environmental, health and safety requirements, and company quality standards. The role supports safe, compliant, and efficient execution of chemical processing, equipment operation, material handling, cleaning, and manufacturing documentation.

Please note this position requires full‑time on‑site presence.

• Execute assigned manufacturing operations according to approved batch production records, SOPs, work instructions, and safety procedures.
• Operate, monitor, and clean API production equipment, including reactors, filter dryers, centrifuges, dryers, mills, blenders, vacuum systems, transfer systems, and associated utilities, as applicable.
• Perform chemical charging, dispensing, weighing, solution preparation, reaction processing, filtration, washing, drying, milling, blending, and packaging activities.
• Verify raw materials, intermediates, solvents, labels, quantities, equipment status, and line clearance requirements before use.
• Monitor critical process parameters such as temperature, pressure, vacuum, agitation speed, flow rate, pH, nitrogen purge, reaction time, and equipment operating conditions; promptly report abnormalities.
• Collect in-process samples or support sampling activities in accordance with approved procedures and coordinate sample submission to Quality Control, where assigned.
• Perform routine in-process checks, including visual inspections, weight verification, pH checks, moisture testing, sieve checks, and yield calculations, as applicable.

• Follow cGMP principles, data-integrity requirements, and good documentation practices at all times.
• Record information contemporaneously, accurately, legibly, and completely; never backdate, overwrite, or obscure manufacturing data.
• Escalate…