Research Scientist III

Role

Research Scientist III at Grifols.

The Immunoassay Research and Development group at Grifols Diagnostic Solutions in Emeryville, CA is seeking an experienced immunoassay development scientist to develop ultrasensitive assays for multiple commercial indications.

• Plans multifaceted projects and incorporates multiple experimental approaches appropriately.
• Leads and carries out immunoassay design, development, and validation using novel and commercial recombinant proteins for multiple indications and commercial applications.
• Leads selection and bioconjugation of recombinant proteins to develop reagents and tools for immunoassays.
• Evaluates protein stability, stoichiometry, and purity using modern analytical techniques and develops protein, reagent and assay formulations.
• Develops assay product prototypes for multiple indications and transfers them to process development and manufacturing teams.
• Independently or with team members, plans R&D projects requiring initiative and judgment within defined procedures and practices.
• Independently selects methodological approaches and specific methods to achieve project objectives.
• Exercises judgment and initiative in making research project decisions. Performs experiments in the laboratory, as needed.
• Identifies, analyzes, and interprets project results. Communicates results and project status to key stakeholders and management.
• Clearly communicates results and project status to key stakeholders and management in a manner that's tailored to diverse audiences.
• Sources and interprets literature and runs database searches to aid in designing experimental studies, troubleshooting experiments, and interpreting findings. Writes original proposals for research projects and remains current on pertinent scientific topics.
• Works cross-functionally and leads collaborations within and outside of R&D, external partners, and/or CROs.
• Prepares written reports on all phases of laboratory experimental projects.
• Authors or co-authors scientific papers and/or journal articles and technical reports.
• Reviews and edits pertinent regulatory documents.
• Prepares and defends patent disclosures and applications.
• May mentor, train or manage other R&D technical staff.
• Attends and participates in scientific meetings, seminars and leadership team meetings.
• Partners and collaborates with small teams in a scientific development environment.
• Plan and prioritize activities while anticipating risks and challenges, monitor progress, and deliver projects to meet timelines and milestones.

• Background in protein biochemistry, structural biology, or protein biophysics.
• Subject matter expert in immunoassay development and validation, including antibody development and screening, ELISA, western blot, immunostaining, BLI.
• Experience with DOE for buffer formulation and relevant software packages.
• Experience bringing tests for FDA and/or EU approval is a plus.
• Experience in method development and optimization of antibody/antigen modification, bioconjugation and coupling onto solid phases; experience with magnetic particles is a plus.
• Analytical assay development, qualification and validation requirements to comply with current regulatory standards.
• Ability to operate laboratory equipment, that may include BLI, DLS, ELISA, and protein quantification platforms.
• Ability to become familiar with relevant scientific literature and represent the research team at meetings and deliver concise scientific presentations.
• Comfortable with handling biohazardous and infectious samples.
• Excellent interpersonal and communication skills and experience working in collaborative settings.
• Data analysis, project planning, judgement in making project decisions.
• Management experience or experience in supervising laboratory training with interns, graduate students, technical staff or post‑doctoral students is highly preferred.
• Experience leading projects and achieving project milestones is highly preferred.
• Experience with immunology, infectious diseases, and oncology is highly preferred.
• Background in immunology and infectious diseases is a plus.
• Background in establishing and utilizing large databases is a plus.

PhD. degree in Biochemistry, Chemistry, Microbiology, Biology or other life science field.

8+ years laboratory experience post Ph.D.

Depending on the area of assignment, directly related experience or a combination of directly related education and experience and/or competencies may be considered in place of the stated requirements.

The estimated pay scale for Research Scientist III role based in Emeryville, California is $144,000 to $180,000. Additionally, the position is eligible to participate in up to 15% of the company bonus pool. Benefits include medical, dental, vision, PTO, up to 5% 401(k) match and tuition reimbursement.

This job description is intended to present the general content and requirements for the performance of this job. It is not an exhaustive…