Registered Nurse Clinical Research Lead

Posted 06/13/2025

Responsible for the implementation and conduct of clinical trials with investigational anti-cancer agents, in collaboration with physicians. Oversight of program development, operational conduct, research account management, and adherence to FDA and other research-related regulatory guidelines.

Requirements:

• 3 to 5 years of direct experience
• BSN
• RN license - NH or other Compact State
• Clinical Research Certification

Responsibilities:

• Collaborate with attending physicians and principal investigators to identify appropriate clinical trials and recruit eligible patients. Work with Cancer Center nursing staff to provide nursing care to patients receiving therapy on clinical research trials. Ensure nursing staff understands how to administer investigational agents per protocol.
• Assist Principal Investigators (PI) in obtaining adequate informed consent. Coordinate study enrollment, protocol treatment, and follow-up care for trial participants.
• Ensure blood sampling and specimen preparation are performed per protocol. Monitor results and ensure correct drug dosing and sample collection times. Oversee scheduling of laboratory and radiologic assessments, admissions, and clinic visits.
• Document all aspects of study and therapy in the electronic medical record and other required databases. Assess patients for therapy-related complications and communicate findings to the medical team and study sponsor.
• Provide in-service training and serve as a resource for clinical staff, including physicians, nurse practitioners, nurses, pharmacists, and allied health professionals. Educate patients about research, their specific trials, HIPAA regulations, and related topics.
• Communicate with referring and affiliated physicians to document clinical findings throughout trials.
• Maintain a database of current and prospective trial patients, ensuring accurate data collection and documentation. Participate in audits and reviews of clinical trials.
• Attend tumor board, IRB meetings, multidisciplinary clinics, and participate in the Cancer Committee. Prepare and submit IRB documentation and present updates.
• Collaborate with department leaders and PIs to support research objectives, develop strategic goals, and improve operational processes. Ensure study compliance with SOPs and maintain research documentation such as NCI RCR registrations.
• Facilitate trial contracting and budget negotiations with sponsors. Handle vendor and site payments, billing, and accounts receivable following contractual terms.