Director, Medicinal Chemistry
Job in
Fort Worth, Tarrant County, Texas, 76102, USA
Listed on 2026-10-09
Listing for:
Scorpion Therapeutics
Full Time
position Listed on 2026-10-09
Job specializations:
-
Pharmaceutical
Drug Discovery, Pharmaceutical Science/ Research, Medicinal Chemist
Job Description & How to Apply Below
Lead medicinal chemistry efforts within a CNS GPCR drug discovery program, guiding small‑molecule candidate progression from hit-to-lead to IND-ready.
Responsibilities- Manage internal and CRO-based chemistry teams, prioritize work, resolve synthetic challenges, and develop new molecules aligned with target profiles
- Contribute to strategy and IP development
- Analyze SAR and ADME data
- Leverage structure‑based design and computational tools
- Communicate findings to multidisciplinary teams
- BS/MS in Chemistry
- PhD preferred
- 10+ years in medicinal chemistry, with leadership experience, especially in biotech/pharma
- Expertise in CNS targets, drug discovery stages, synthetic chemistry, pharmacology, ADME, and IP
- Proven ability to lead remote teams and manage outsourced chemistry vendors
- Strong problem‑solving, innovation mindset, and effective communication skills
- CNS
- neurodegenerative or sleep‑wake disorders
- small molecules
- hit‑to‑IND progression
- experience with digital tools and AI in drug discovery
Remote with occasional travel; salary $150K-$210K plus bonus and benefits.
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