Sr. Research Associate; Protein Therapuetics

Sr. Research Associate (Protein Therapuetics)

Gilead Sciences currently has an exciting opportunity for a highly motivated Sr. Research Associate to join our protein purification, QC, and logistics group within the Protein Therapeutics Department. The successful candidate is expected to work independently and display professional judgment in all aspects of daily research and presentations. This person will work in collaboration with research project teams to generate and validate potential therapeutic proteins, surrogate tool molecules, and bioconjugates.

• Perform protein purification, conjugation, QC, and sample bank registration to support the preclinical development of biopharmaceutical programs across multiple therapeutic areas.
• Prepare technical reports, quantitative analyses, and summaries for entry into Excel, PPT, and ELN formats.
• Use good oral and written communication skills to relay scientific data.
• Actively participate in group meetings, present the results of one’s work, interpret data, and draw conclusions regarding presented material and maintain awareness of cutting‑edge technical developments and scientific knowledge and apply these where possible to improve process efficiency.

BS in Biology, Biochemistry, Chemistry or related field with at least 2 years of relevant experience OR MS with relevant experience with below listed characteristics and techniques for the position.

• Strong background in protein sciences and protein biochemistry.
• Direct industry experience in purifying and characterizing a variety of recombinant proteins, particularly monoclonal antibodies and next generation biologics (e.g., bispecific antibodies, immunocytokines).
• Hands‑on experience in purification techniques including affinity, ion exchange, size exclusion, hydrophobic interaction chromatography using Akta Avant/Pure or Bio Rad NGC.
• Hands‑on experience in protein conjugation technologies (e.g., NHS chemistry, malemide chemistry, enzymatic conjugation) and the related QC.
• Proficiency with various analytical protein characterization techniques such as SEC‑HPLC or UHPLC, SDS‑PAGE, Endosafe.
• Ability to perform method development and write protocols.
• Proficiency in editing and writing AKTA methods using Unicorn software.
• Detailed record‑keeping is a must.
• Ability to multi‑task and work in a fast‑paced team environment.
• Must be team‑oriented, professional, hard‑working, and interested in learning new skills.
• Ability to analyze and present experimental data with proper software and other necessary tools.

• Experience in conjugation and characterization of ADC (antibody drug conjugate) would be a plus.
• BS in Biology, Biochemistry, Chemistry with at least 2 years of relevant experience preferred.
• MS in Biology, Biochemistry, Chemistry with relevant experience preferred.