Therapeutics Discovery Technician

Therapeutics Discovery Technician

Cape Fox subsidiary Eagle Health, LLC is accepting resumes for a Therapeutics Discovery Technician to support the members rick, Maryland. This position is contingent upon contract award.

Incumbents are encouraged to apply!

The salary range (or hiring range) for this exempt position has been established at: $75,000‑$84,000
.

The above salary range represents the company's good faith and reasonable estimate of the range of possible compensation at the time of posting. In addition, we offer a variety of benefits including company holidays, paid time off, health insurance, dental insurance, vision insurance, life and disability insurance, tuition reimbursement, as well as 401(k) with company match. This job will be posted until filled or withdrawn.

The employee shall provide laboratory support for research efforts of the MBD. Support shall be required in BSL‑2 environment. The employee shall provide support in the planning and conduct of basic and applied research on current and emerging threats in support of the BD and infectious disease program. The employee shall aid in the development and execution of scientific studies, basic cell culture, 3D bioprinting, stem cell maturation, spheroid/organoid development, PCR, high‑throughput screening assays and/or high‑throughput sequencing on infectious agents.

Some other assays, such as animal procedures, collection/data analyzing, and maintaining laboratory equipment may be required.

• Assist in the planning, development, execution and evaluation of high‑throughput screening projects for antibacterial, anti‑viral, and anti‑toxin therapeutic areas and assist in the development of novel assays/methods for various programs. This includes basic cell culture, stem cell maturation, 3D bioprinting, and spheroid/organoid development to support these efforts. Shall assist in screening of molecular compound libraries for therapeutic efficacy to support MCM development.
• Perform both in vitro and in vivo microbiological experiments designed to evaluate therapeutic compounds for antibacterial/antiviral/antitoxin activity. In vitro assays include enzymatic assays, cell‑based phenotypic and reporter assays, Minimum Inhibitory Concentration (MIC) and plaque assays. Shall perform basic and advanced molecular biology techniques such as gene cloning, gel electrophoresis (DNA/RNA gels and Western blots) and transcriptomics (10X genomic for bulk and spatial transcriptomics).
• Support BSL‑2 mouse studies when required. Shall assist with inoculations of animals, collect specimens for processing, and analysis of those specimens. Analysis may include development and conduct of immunological procedures including Enzyme‑Linked Immunoassay (ELISA), Western blot, and Mesoscale Discovery assays.
• Assist in the preparation of technical reports, standard operating procedures, and manuscripts relating to research efforts. The employee may be expected to present research findings at one scientific conference per year as needed and CONUS travel may be required. Employee shall present results in written and oral format publicly and internally as requested.
• Be responsible for assessing and maintaining laboratory supplies in BSL‑2 laboratories. Shall assess supplies and ensure orders are coordinated with Division resources. Shall ensure that all assigned laboratory space is orderly and compliant with all regulatory guidance.
• Perform operations and training in animal manipulations. Employee shall support BSL‑2 animal studies (mouse, hamsters, guinea pigs, etc.) for funded projects. Employee shall be experienced with handling both bacterial and viral pathogens for in vitro and in vivo studies.
• Provide the TPOC a Research Technical Report no later than the last day of each month.
• Communicate to the Lead/PI or assigned TPOC unexpected experimental data/results and assist in troubleshooting or root‑cause analysis. Employee shall communicate laboratory or other task‑related issues to the TPOC and coordinate with internal maintenance or external vendors for technical support and troubleshooting.
• Maintain an orderly laboratory environment in compliance with…