Postdoctoral Scientist - Sharma Lab - Regenerative Medicine Institute

Postdoctoral Scientist - Sharma Lab - Regenerative Medicine Institute at CEDARS-SINAI summary:
The Postdoctoral Scientist in the Sharma Lab at Cedars-Sinai Regenerative Medicine Institute conducts advanced research using human induced pluripotent stem cells, CRISPR technology, and cardiac organoids to study cardiovascular diseases and drug toxicities. The role includes designing experiments, data analysis, mentoring, and contributing to publications under the guidance of the principal investigator. This position focuses on cutting-edge regenerative medicine with potential applications in cardiac disease modeling, drug toxicity prediction, and space biology.

Job Description
Join Dr. Arun Sharma and his research group as a Postdoctoral Scientist in the Cedars-Sinai Regenerative Medicine Institute!
The Sharma Laboratory at Cedars-Sinai Medical Center, Regenerative Medicine Institute is looking for personnel to join our new and dynamic group. The mission of the Board of Governors Regenerative Medicine Institute aims to prevent and treat the world's most prevalent diseases through cell revitalization and transplantation. Work in the laboratory of Arun Sharma, PhD, focuses on applying human induced pluripotent stem cells (hiPSCs) to model cardiovascular diseases in vitro.

The lab utilizes cutting-edge technologies, including hiPSCs, CRISPR/Cas9 genome editing, cardiac microfluidic organ-chips and cardiac organoids in our studies. Specifically, we have used hiPSC-derived cardiomyocytes (heart muscle cells) to model cardiac viral infections during COVID-19, examine developmental mechanisms underlying congenital heart disease and understand ways to alleviate cardiac toxicity caused by cancer drugs. In our ongoing studies, we have a unique background and interest in space biology, notably exploring ways in which stem cell biology can intersect with this emerging field.

To learn more, please visit Sharma Research Lab | Cedars-Sinai.
Are you ready to be a part of breakthrough research?
Under the direction of Dr. Arun Sharma, the incumbent will be a part of a new collaborative project recently funded by ARPA-H, on the topic of predictive modeling of drug toxicities using pluripotent stem cells. The Postdoctoral Scientist may develop, adapt, and implement new research techniques and protocols, and will analyze, compile, and interpret data.
Primary

Job Duties and Responsibilities:

• May assist in preparation of grant proposals, submissions, publications and presentations but is not responsible for generating grant funds.

• Participate in publications and presentations as author or co-author.

• Designs and performs experiments, especially in regards to stem cell culture.

• Keeps appropriate experimental records and documentation and analyze the results with the Co-Principal Investigator.

• May mentor/train research associates, technicians, and students.

• Participation in laboratory meetings, keeping a lab notebook, performing calculations, tabulating data, summarizing methods and results of related experiments, and general lab maintenance.

• Operates and maintains equipment and instruments.
Qualifications

Education:

• Doctorate (MD, PhD, VMD, or DDS) in area directly related to field of research specialization.

Experience and Skills:

• Acquires technical and theoretical knowledge of research project and objectives during one to fiveyear post-doctoral appointment.

• Works independently on research projects designed by a mentor (typically the PI) within area of specialization.

• Demonstrated skills to perform experimental protocols and procedures, including detailed data collection, and analysis.

• Experienced in research animal husbandry and handling.

• Scheduling flexibility including evening, weekend and holiday rotation commitment may be necessary. Travel may be required.

• Function efficiently and cooperatively with a team of faculty, research associates, technicians, and students.

• Excellent written and oral communication skills are essential.

• Knowledge of safety standards and maintenance of specialized equipment.
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