Bioinformatics Research Scientist; II or III

Job No: 541473

Work Type:
Full Time

Location:

Main Campus (Gainesville, FL)

Categories:
Biology/Life Science, Computer Science, Physical/Mathematical Sciences

Department:  - HA-UFHCI BIOSTAT COMP BIOL SR

Classification

Title:

Bioinformatics Analyst II/III

• Bioinformatics Analyst II: A bachelor's degree in an appropriate area of specialization and two years of experience.
• Bioinformatics Analyst III: A master's degree in appropriate area of specialization and two years of experience or a bachelor's degree and four years of experience.

The University of Florida Health Cancer Institute (UFHCI) is an NCI-designated cancer center comprising more than 350 basic, translational, and population-based scientists and clinicians who conduct research for the prevention, diagnosis, and treatment of cancer. A central collaborative research model encourages translation of basic laboratory findings into novel therapies, and the multidisciplinary membership of the Institute is its strength. Researchers are drawn from across UF, including six colleges within the Health Science Center — Medicine, Nursing, Dentistry, Pharmacy, Public Health and Health Professions, and Veterinary Medicine — as well as the Colleges of Liberal Arts and Sciences, Engineering, Health and Human Performance, Journalism and Communications, and Agricultural and Life Sciences.

Research is organized around four programs:
Cancer Control and Population Sciences;
Cancer Targeting and Therapeutics;
Immuno-Oncology and Microenvironment; and Mechanisms of Oncogenesis.

UFHCI invites applications for both a Doctoral- and Masters-level bioinformatics research scientist in the Biostatistics and Computational Biology Shared Resource (BCB-SR). The position reports to the Associate Director for Cancer Quantitative Sciences and Director of the BCB-SR and works within the Bioinformatics Unit alongside biostatisticians and other computational scientists.

The Bioinformatics Unit provides analytical support to UFHCI members. The successful candidate will work directly with cancer researchers from experimental design through analysis, interpretation, and publication. The position carries a broad and changing project portfolio, substantial investigator contacts, and regular co-authorship on peer-reviewed publications.

• Analyze high-throughput genomics data in support of UFHCI investigators, including bulk and single-cell RNA-seq, ATAC-seq, DNA methylation assays (WGBS, EM-seq, RRBS), ChIP-seq, and whole-genome or whole-exome sequencing.
• Consult with investigators on experimental design, feasibility, and analysis plans before data are generated, and contribute analysis plans, preliminary data, and written text to grant applications.
• Develop, adapt, and maintain reproducible analysis pipelines and software on UF's Hi Per Gator  high-performance computing cluster, using workflow managers, containers, and version control.
• Integrate multi-omic, clinical, and publicly available data sets; develop or adapt statistical and computational methods where existing tools are inadequate.
• Interpret results in collaboration with investigators and contribute figures, methods sections, and manuscript text to publications and presentations.
• Maintain organized project documentation, code repositories, and data management practices, and track service requests and effort for shared-resource reporting.
• Contribute to training and outreach for cancer center members and trainees, including workshops, tutorials, and individual instruction.
• Maintain current knowledge of the field through seminars, journal clubs, and scientific meetings, and evaluate…