Process Development Scientist; Molecular Biology *PC

At Miltenyi Biotec, 3,000 employees worldwide develop pioneering solutions for biomedical science and the clinical application of cell therapies. Our multidisciplinary team combines excellence in research with the development of innovative products for the treatment of serious diseases.

Your Tasks:

As a member of the Lentigen Technology Molecular Services team, you will have the exciting opportunity to support the development and characterization of Lentiviral vectors. You will apply your exceptional interpersonal and organizational skills to serve as a cross-functional team liaison to successfully coordinate and execute Molecular Services team activities to accomplish department objectives. As a PD Molecular Biology Scientist, you will play a key role in driving the development of new products and technologies.

Essential Duties and Responsibilities:

• Work in a matrixed environment and effectively communicate with multiple departments to support lentiviral vector development and characterization.
• Provide molecular biology expertise to the Molecular Services team to develop and implement proper study design to include plasmid assembly, restriction enzyme digest, PCR and sequencing primer design, and Sanger sequencing analysis.
• Knowledge of molecular biology software to perform in silico cloning and plasmid sequence analysis, including but not limited to selection of restriction enzymes and primer design.
• Design and execute experiments to support the development of lentiviral vectors, including strategies for vector backbone optimization.
• Utilize a variety of molecular biology techniques, including cloning, PCR, qPCR and ddPCR.
• Perform data analysis including, but not limited to, restriction digest analysis, Sanger sequencing data analysis, and sequence alignments.
• Contribute to the preparation of technical reports and presentations to internal and external stakeholders.
• Excellent organizational and documentation skills will be instrumental in the tracking and communication of data and will ensure efficient progress towards achieving team objectives.

Requirements:

• PhD; or Master’s in Molecular Biology, Virology or relevant field with at least 5 years of related experience or bachelor’s degree with 10 years of relevant experience; or equivalent combination of education and experience.
• Expertise in lentivirus vectors design and optimization of vector backbones
• Solid understanding in experimental design and molecular biology methodologies
• Strong hands-on experience with molecular biology techniques, including plasmid assembly, PCR, qPCR and ddPCR
• Understanding of common analytical methods used in Biotechnology labs is a plus but not necessary (Immunoassays, Cell based titer, Flow Cytometry, etc.)
• Excellent interpersonal skills to successfully communicate with multi-disciplinary teams.
• Strong documentation, organizational, and writing skills enabling capability to provide summaries and reports.
• Highly motivated, fast learner, detail-oriented team player. Good organization, initiative, and a collaborative attitude are essential.
• Please note that this position may require vaccination against COVID-19, unless individual is entitled to reasonable accommodation under applicable law.

Physical Demands:

The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. While performing the duties of this job, the employee is regularly required to walk; use hands to finger, handle, or feel;

reach with hands and arms, talk, and hear. The employee is required to stand; climb or balance and stoop, kneel, crouch. The employee must occasionally lift and/or move up to 50 pounds. Specific vision abilities required by this job include close vision, color vision, peripheral vision, depth perception and ability to adjust focus. Must have ability to handle more than one task at a time and must work at a rapid pace while maintaining attention to detail.

The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. This job is performed in a temperature controlled facility without exposure to extreme hot or cold temperatures. Generally, this job is performed in a sanitized laboratory setting and routinely uses standard medical and research equipment such as centrifuges, biosafety cabinets, chromatography devices and columns, tangential-flow filtration devices and filters, peristaltic pumps and metering fill pumps, pipettes and computers.

While performing the duties of this job, the employee is frequently exposed to blood, viruses, bacteria, body fluids and other tissues. Employees entering and leaving the laboratory must wear appropriate…