Senior Scientist - Protein Expression Sciences

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a highly motivated Senior Scientist to join our Protein Expression Sciences Department. In this role, you will create antibody production cell lines using state-of-the-art mammalian expression technologies and develop new technologies to further advance our expression platform, while collaborating with cross-functional scientific teams.

This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

• Location:
  
  Tarrytown, NY
• Work model:
  On-site

• Apply innovative mammalian expression technologies to generate regulatory-compliant stable cell lines
• Perform aseptic cell culture, handling, and transfection of cell lines
• Conduct flow cytometry assays and operate liquid handler platforms (Hamilton) to analyze stable cell lines
• Perform molecular biology and protein biochemistry techniques, including PCR, RT-PCR, plasmid sub-cloning, isolation of genomic DNA and RNA from CHO cells, SDS-PAGE, and western blotting
• Independently design, conduct, and analyze multicolor flow cytometry experiments
• Analyze and present data at smaller team and broader department meetings
• Maintain complete, accurate, and timely records of experiments and data analysis

• PhD with 0-3 years of postdoctoral experience, or BS/MS with 4-8 years of experience, in Immunology, Cell Biology, or Molecular Biology
• Hands‑on technical experience in cell culture, flow cytometry, and antibody staining
• Experience with molecular biology techniques such as PCR and cloning
• Passion for innovation and a desire to lead new scientific directions
• Working independently, demonstrating strong problem‑solving skills and the ability to manage multiple tasks efficiently without direct supervision
• Strong desire to develop your skills and work with a cross‑functional team and the ability to thrive in a collaborative, fast‑paced environment
• Experience with gene editing, lentivirus infections, CRISPR library workflows, and NGS is a plus

Does this sound like you? We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law.

Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and…