Director Statistical Genetics; Oncology
Listed on 2026-10-08
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Science
Research Scientist, Clinical Research, Medical Science, Genetics / Genomics
Location: Tarrytown
We are seeking an exceptional senior leader with deep expertise in cancer genetics and genomics to join our team at the Regeneron Genetics Center. This Director-level role carries full accountability for the strategy and execution of cancer genetic product development — from aligning the vision with senior leadership and translating it into an actionable operational plan, through overseeing product development and setting the strategy for commercialization.
The ideal candidate will bring a demonstrated track record of independence and impact, and will serve as the driving force for bringing cancer risk genomics into clinical and commercial reality.
- Develop and deliver on cancer genetics testing opportunities, including germline testing partnerships, serving as the senior leader accountable for clinical cancer test development.
- Define and own the end-to-end strategy for germline genetic cancer risk product development, translating organizational vision — aligned with senior leadership — into a clear, actionable operational roadmap with measurable milestones.
- Develop and execute a comprehensive somatic genetics strategy for Regeneron’s oncology portfolio, identifying new opportunities for somatic profiling studies across tumor types and leveraging existing cancer genomics databases.
- Lead and execute large-scale somatic cancer sequencing analyses, including whole-exome and whole-genome sequencing of tumor samples, RNA-seq, and integrative multi-OMICS studies to identify driver mutations, therapeutic vulnerabilities, and mechanisms of resistance.
- Design and contribute to cancer molecular profiling and clinical correlation analyses that integrate germline and somatic mutational profiles with multi-modal transcriptomic, epigenetic, and proteomic data to support target discovery, indication selection, and patient stratification strategies.
- Oversee all phases of product development for cancer risk genomics programs, ensuring scientific rigor, cross-functional alignment, and on-time delivery against strategic objectives.
- Develop and execute the commercialization strategy for RGC cancer products, identifying market opportunities, go-to-market pathways, and partnerships that maximize clinical and commercial impact.
- Collaborate with and lead a multidisciplinary genetics team consisting of human genetics scientists, bioinformaticians, and statistical geneticists to design, execute, and interpret genetics studies related to cancer risk, somatic evolution, mechanisms, and therapeutic outcomes.
- Have a demonstrated ability to independently own and drive strategic programs in cancer risk genomics or oncology product development from conception through commercialization.
- Bring innovative thinking and hands-on leadership to large-scale somatic cancer sequencing studies and integrative genomic analyses.
- Have deep expertise in analyzing tumor sequencing data, including variant calling, mutational signature analysis, clonal evolution, copy number alterations, and structural variant detection.
- Have experience in developing or contributing to germline diagnostic tests for cancer predisposition, risk assessment, or clinical decision-making.
- Are a motivated senior leader with a desire to pursue genetic discovery in a fast-paced multidisciplinary environment and can effectively guide teams and align stakeholders toward strategic goals.
- Have demonstrated experience in quantitative problem solving, statistical analyses, and translating somatic and germline genetic findings into clinical applications.
you must have an MD or MD/PhD with a strong background in quantitative biology applied to cancer genetics and…
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