Principal Clinical Scientist

Principal Clinical Scientist (AI Training) About The Role

What if your deep expertise in clinical trial design and regulatory science could directly shape how AI understands and reasons about biomedical evidence? We're looking for a Principal Clinical Scientist to bring senior-level rigor to AI-driven research workflows - ensuring the clinical data powering next-generation AI systems meets the standards expected in real-world regulatory submissions.

This is a fully remote, flexible contract role built for experienced clinical scientists who want to work at the cutting edge of AI without leaving their field behind.

• Organization:
  Alignerr
• Type:
  Hourly Contract
• Location:
  
  Remote
• Commitment: 10-40 hours/week

• Design and review clinical trial protocols used to generate high-quality, regulator-ready datasets for AI training and evaluation
• Interpret and audit clinical trial results to ensure accuracy, consistency, and regulatory relevance
• Evaluate AI-generated clinical analyses for scientific soundness and alignment with FDA, EMA, or equivalent regulatory expectations
• Provide expert feedback that directly improves how AI models reason about clinical trial data, endpoints, and outcomes
• Help set the standard for how clinical evidence is structured, assessed, and applied within frontier AI systems

• Senior-level clinical scientist with substantial experience designing trial protocols for regulatory submission
• Deep expertise interpreting clinical data for major regulatory agencies (FDA, EMA, or equivalent)
• Strong grounding in clinical research methodology, biostatistics, or translational science
• Rigorous and detail-oriented - you can spot a flawed endpoint or a data inconsistency that others would miss
• Comfortable working independently and asynchronously in a remote, task-based environment

• Prior experience with data annotation, data quality review, or AI evaluation workflows
• Background in pharmacology, epidemiology, or medical writing
• Familiarity with AI tools or research platforms as an end user

• Work directly on frontier AI systems that are reshaping clinical and biomedical research
• Fully remote and flexible - structure your hours around your life
• Freelance autonomy with the substance of genuinely meaningful, expert-level work