Senior Scientist; Molecule Protein

200 staff. Limitless Potential. One team.

Cancer Research Horizons.

Senior Scientist (Small Molecule Proteins)

£41,700 - £51,300plus benefits

Department:
Therapeutic Innovation, R&I

Reports to:

Principal Scientist

Location:

CRUK Scotland Institute, Glasgowwith Low flex (Lab Based)

Contract type/hours: X2 Permanent Contracts, Full time 35 hours per week

Closing date: 1st March 2026 23:55pm

Interview Date:
Approximately week commencing 9th March

Interview process:
Competency based interview with task/presentation

At Cancer Research UK, we exist to beat cancer.

Wehave an exciting opportunity for two Senior Scientists in smallmolecule protein sciences to join Cancer Research Horizons in our Glasgow lab. You’lllead the expression, purification and QC of protein antigens and related molecules,all ofwhichplay a critical role indriving our screening and crystallography programmes.

Workingprimarilyacross bacterialandinsectsystems,you’lldeliver high quality, wellcharacterised proteins using a range of biochemical and biophysical methods.

You’ll collaborate closely with multidisciplinarydrug discoveryteams, communicate insights clearly,drive strategic decisions, innovate across the existing pipeline,bring strong scientific leadership the team,andhelp ensure a safe, efficient lab environment.

We’relooking for candidates with a PhD (or equivalent experience) in Molecular/Protein Sciences, Chemistrywithsubstantialdrug discoveryexperience, with strongproteinproduction,purification,analytics, and molecular biologyexpertise.

This is a high impact role that advances our discoveries. Ifyou’readaptable, driven, and ready to make a scientific impact, this is your chance to contribute.

Every role at CRH is united by a single mission: beating cancer sooner. We carry out work that matters-impactingpatients, families, and the future of science.

About Cancer Research Horizons

As the world’s biggest medical research charity,we’vehelped bring eleven new cancer drugs to market. However, there is still an urgent need to bring more effective treatments to patients faster.

We have recently developeda new approach to driving therapeutic innovation through the creation of Cancer Research Horizons (CRH). We have brought together Cancer Research UK’s established drug discovery teams under one organisation and leadership team, combining our unique pipeline of cancer biology expertise and access to CRUK’s world-class academic network, cutting edge technology platforms and clinical expertise to
1)
Bring new treatments to patients faster and
2)
Tackle the biggest challenges in discovering cancer drugs by seeking out more radical ideas and embracing risk in our bid to achieve success.

Based at sites in Cambridge, the CRUK Scotland Institute in Glasgow, and Newcastle University,you’llbe joining over
200 staff from both industrial and academic backgrounds, all dedicated to bringing forward the day we cure cancer.

• Expression and purification of recombinant proteins using bacterialandinsect systems to support screening and crystallography programmes– experience of mammalian protein expression would also be desirable
• Ensure all production is sufficiently characterised and QC’d using appropriate biochemical and biophysical methods
• Interpret, analyse and clearly summarise data for presentation to varied audiences
• Work collaboratively within multidisciplinary research teams
• Communicate effectively, demonstrating openness and respect for others’ perspectives
• Prioritise workload according to project objectives and take responsibility for timely delivery
• Drive scientific and technical innovation, including through internal and external collaborations, while staying current with developments in the field
• Maintain accurate and up-to-date electronic laboratory notebook records
• Take responsibility for assigned laboratory equipment and associated duties
• Uphold safe, compliant and effective working practices

• PhD or equivalent in Molecular Sciences, Protein Sciences, Chemistry or significant experience within a drug discovery environment
• Significant experience in providing protein & molecular biology expertise to enable drug discovery projects
• De…