Specialist - Research

Position Summary

The laboratory of Dr. Michael R. Williams at the Grand Rapids Research Center in the Department of Pediatrics and Human Development, is soliciting applications for the position of Specialist - Research. The incumbent will be expected to take a lead role on biomedical research projects focused on the creation and evaluation of genetically encoded tools to analyze the structure and function of neural circuits in research subjects.

Responsibilities include:

• Assisting in molecular biology techniques, primarily the cloning of recombinant DNA plasmids
• Assisting in the preparation, organization, and evaluation of replication deficient viral vectors
• Maintaining a transgenic mouse colony, including breeding, weaning, and genotyping
• Conducting survival procedures on the same including stereotaxic surgery and other injection paradigms.
• Conducting terminal procedures including transcardial perfusion for live or fixed brain tissues
• Conducting patch clamp electrophysiology of neurons and their connected populations
• Conducting histological procedures for the preparation and evaluation of fixed brain tissues by fluorescent microscopy
• Conducting data analysis, assist authoring manuscripts and grants, manage trainees, and maintain compliance with health and safety practices in the laboratory

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, citizenship, age, disability or protected veteran status.

Doctorate
-Biology or a related field

PhD or DVM and at least five (5) years of experience at the level of proficient independence in:

• All aspects of neuronal patch-clamp electrophysiology
• Survival procedures in mice including stereotaxic surgery
• Maintenance of complex transgenic rodent colonies
• Preparation of fixed tissues for evaluation by fluorescent microscopy

Candidates must also demonstrate a track record of peer reviewed, published research, and a basic background in recombinant DNA cloning methods.

• Cover Letter
• CV

11/10/2025

• Work with animals or unfixed animal tissue.

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