Protein Scientist

Job Title

Protein Scientist

Piramal Pharma Solutions is a contract development and manufacturing organization (CDMO) offering end-to-end development and manufacturing solutions across the drug life cycle. We serve clients through a globally integrated network of facilities in North America, Europe and Asia, enabling a comprehensive range of services including Drug Discovery Solutions, Process & Pharmaceutical Development, Clinical Trial Supplies, and Commercial supply of APIs and Finished dosage forms.

We also offer specialized services such as development and manufacture of Highly Potent APIs and Antibody Drug Conjugation.

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To carry out laboratory experimentation to support Technology Transfer, Development and Siting of new processes for GMP, and to assist in manufacture.

• Design and execute experiments for the expression of recombinant proteins in various host systems (e.g., bacterial, insect, mammalian cells).
• Develop and optimize protein purification strategies using chromatographic techniques (e.g., affinity, ion exchange, size exclusion).
• Perform biophysical and biochemical characterization of purified proteins to assess purity, integrity, activity, and stability (e.g., SDS-PAGE, Western blot, mass spectrometry, DLS, SEC-MALS, thermal denaturation assays).
• Contribute to the design and execution of protein engineering experiments to improve protein properties or function.
• Maintain detailed and accurate records of experimental procedures, results, and data analysis.
• Interpret experimental data, troubleshoot technical issues, and present findings to internal teams.
• Collaborate with colleagues across disciplines, including molecular biology, assay development, and structural biology.
• Stay current with scientific literature and new technologies in the field of protein science.
• Adhere to safety regulations and good laboratory practices.

• Ph.D. in Biochemistry, Molecular Biology, Protein Science, or a related field with 0-3 years of relevant industry experience, or an M.S. with 3-5 years of relevant industry experience.
• Proven expertise in protein expression systems (e.g.,
  
  E. coli, baculovirus/insect cells, mammalian cells).
• Extensive hands-on experience with protein purification techniques (e.g., ÄKTA FPLC systems, affinity chromatography, ion exchange, SEC).
• Proficient in protein characterization methods (e.g., SDS-PAGE, Western blot, mass spectrometry, DLS, fluorescence spectroscopy).
• Strong understanding of protein structure–function relationships.
• Excellent problem-solving skills and the ability to work independently as well as part of a team.
• Strong written and verbal communication skills.
• Ability to manage multiple projects simultaneously and meet deadlines.
• Experience with protein engineering techniques is a plus.
• Familiarity with pharmaceutical drug discovery and development processes is desirable.