Scientist, Pharmaceutical Science​/ Research, Validation Engineer

Job Title:

Scientist

Location:

Hamilton, Ontario

Onsite 5 days/week

Fusion Pharmaceuticals, part of the AstraZeneca Group, is redefining precision oncology with next‑generation radio conjugates that deliver powerful alpha‑emitting payloads directly to tumors. Our pipeline spans multiple first‑in‑class programs—backed by a GMP‑compliant, brand new radiopharmaceutical facility in Hamilton, we’re turning groundbreaking science into real‑world impact for patients. Join us at the forefront of radiopharma innovation and be part of turning breakthrough science into meaningful outcomes for patients—come build what’s next with us!

Fusion Pharmaceuticals is opening the role of Scientist to support the design of manufacturing and analytical processes as well as the technology transfer, in‑house and with CDMO partners. This role will report to the Associate Director of Process Development and Technology Transfer and requires collaborative skills, multi‑tasking ability, and the desire to strive in a fast‑paced environment. The successful candidate will bring a strong background in radio labelling, radiometal chemistry and analytical method development, and have knowledge of manufacturing within the biotech or pharmaceutical industry.

• Build and complete the laboratory work and tasks related to the development of manufacturing and analytical processes for targeted alpha therapies and related compounds.
• Analyze generated data and report outcomes to the project’s teams.
• Lead or support the technology transfer of newly designed manufacturing and analytical processes.
• Generate supporting documentation for newly designed processes such as development reports, standard operating procedures (SOP), work instructions, validation documentation (e.g.: process and equipment validation, validation report).
• Participate in validation and qualification activities for new clinical manufacturing processes and analytical methods, as necessary.
• Support the CMC group during investigations (non‑conformance, deviation, out‑of‑specification).

• Minimum MS degree with 5+ years of experience in product development and manufacturing, which may include relevant graduate or academic experience;
  Advanced degree in organic or analytical chemistry, radiochemistry, radiopharmaceutical sciences, Pharmaceutical Science, Chemical Engineering, or related scientific discipline.
• Experience in radiopharmaceuticals manufacturing and analytical method development and validation preferred.
• Experience with manufacturing process design using an automated synthesis unit is an asset.
• Knowledge of radiation safety principles/dangerous goods and regulations (e.g. CNSC, NRC).
• Strong interpersonal skills are required, and the successful candidate will work in a cross‑functional team and will be expected to take a leadership position in key manufacturing projects.
• Excellent written and verbal communication skills with an ability to adapt to various partners and geography.
• Meticulous, self‑motivated, decisive, and independent with a willingness to work in a fast‑paced environment.
• Available to travel to various locations (primarily in North America).

• GTAA Top Employer Award for 11 years
• Top 100 Employers Award
• Canada’s Most Admired Corporate Culture
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AstraZeneca is an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. AstraZeneca is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment, assessment and selection process and may be requested by…